Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   H7969_RS11040 Genome accession   NZ_CP060280
Coordinates   2184588..2185286 (+) Length   232 a.a.
NCBI ID   WP_002221583.1    Uniprot ID   A1KRV7
Organism   Neisseria meningitidis strain LNP24198     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2179588..2190286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7969_RS11025 (H7969_11025) trpC 2180669..2181451 (-) 783 WP_002221587.1 indole-3-glycerol phosphate synthase TrpC -
  H7969_RS11030 (H7969_11030) - 2181502..2182458 (-) 957 WP_002221585.1 YheT family hydrolase -
  H7969_RS11035 (H7969_11035) murJ 2182591..2184129 (-) 1539 WP_002221584.1 murein biosynthesis integral membrane protein MurJ -
  H7969_RS11965 - 2184187..2184294 (+) 108 Protein_2143 IS5/IS1182 family transposase -
  H7969_RS11040 (H7969_11040) dsbA1 2184588..2185286 (+) 699 WP_002221583.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  H7969_RS11045 (H7969_11045) amgK 2185343..2186347 (-) 1005 WP_002221582.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  H7969_RS11050 (H7969_11050) - 2186417..2188825 (+) 2409 WP_002247753.1 LPS-assembly protein LptD -
  H7969_RS11055 (H7969_11055) - 2188930..2190144 (+) 1215 WP_186980794.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25236.83 Da        Isoelectric Point: 5.3490

>NTDB_id=475231 H7969_RS11040 WP_002221583.1 2184588..2185286(+) (dsbA1) [Neisseria meningitidis strain LNP24198]
MKSKHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=475231 H7969_RS11040 WP_002221583.1 2184588..2185286(+) (dsbA1) [Neisseria meningitidis strain LNP24198]
ATGAAATCCAAACACCTCGCCCTCGGCGTTGCCGCCCTGTTCGCACTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACTGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTCGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCTTACGAATCTCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTTCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGCAAATATAAAGTCGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KRV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

99.138

100

0.991
  dsbA2 Neisseria meningitidis MC58

76.19

81.466

0.621