Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JTR57_RS07555 Genome accession   NZ_CP070962
Coordinates   1568204..1568860 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain K-12 J53     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1563204..1573860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JTR57_RS07525 dcyD 1564083..1565069 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JTR57_RS07530 tcyL 1565084..1565752 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JTR57_RS07535 tcyN 1565749..1566501 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JTR57_RS07540 sdiA 1566731..1567453 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  JTR57_RS07545 yecF 1567521..1567745 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JTR57_RS07550 yecU 1567732..1567908 (-) 177 WP_000590347.1 protein YecU -
  JTR57_RS23605 - 1567991..1568062 (-) 72 Protein_1475 transcriptional regulator -
  JTR57_RS07555 letA 1568204..1568860 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JTR57_RS07560 uvrC 1568857..1570689 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JTR57_RS07565 pgsA 1570746..1571294 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JTR57_RS07585 yecA 1571944..1572609 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=475201 JTR57_RS07555 WP_000611335.1 1568204..1568860(+) (letA) [Escherichia coli strain K-12 J53]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=475201 JTR57_RS07555 WP_000611335.1 1568204..1568860(+) (letA) [Escherichia coli strain K-12 J53]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486