Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JR909_RS09210 Genome accession   NZ_CP070920
Coordinates   1914572..1915228 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 40EC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1909572..1920228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JR909_RS09180 (JR909_09180) dcyD 1910452..1911438 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JR909_RS09185 (JR909_09185) tcyL 1911453..1912121 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JR909_RS09190 (JR909_09190) tcyN 1912118..1912870 (+) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JR909_RS09195 (JR909_09195) sdiA 1913100..1913822 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  JR909_RS09200 (JR909_09200) yecF 1913889..1914113 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JR909_RS09205 (JR909_09205) yecU 1914100..1914276 (-) 177 WP_000590347.1 protein YecU -
  JR909_RS26085 - 1914359..1914430 (-) 72 Protein_1808 transcriptional regulator -
  JR909_RS09210 (JR909_09210) letA 1914572..1915228 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JR909_RS09215 (JR909_09215) uvrC 1915225..1917057 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JR909_RS09220 (JR909_09220) pgsA 1917114..1917662 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JR909_RS09240 (JR909_09240) yecA 1918312..1918977 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=475046 JR909_RS09210 WP_000611335.1 1914572..1915228(+) (letA) [Escherichia coli strain 40EC]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=475046 JR909_RS09210 WP_000611335.1 1914572..1915228(+) (letA) [Escherichia coli strain 40EC]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486