Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JR901_RS09325 Genome accession   NZ_CP070906
Coordinates   1968717..1969373 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 88COLEC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1963717..1974373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JR901_RS09295 (JR901_09295) dcyD 1964597..1965583 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JR901_RS09300 (JR901_09300) tcyL 1965598..1966266 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JR901_RS09305 (JR901_09305) tcyN 1966263..1967015 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JR901_RS09310 (JR901_09310) sdiA 1967244..1967966 (+) 723 WP_032256217.1 transcriptional regulator SdiA -
  JR901_RS09315 (JR901_09315) yecF 1968034..1968258 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JR901_RS09320 (JR901_09320) yecU 1968245..1968421 (-) 177 WP_001696741.1 protein YecU -
  JR901_RS24945 - 1968504..1968575 (-) 72 Protein_1837 transcriptional regulator -
  JR901_RS09325 (JR901_09325) letA 1968717..1969373 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JR901_RS09330 (JR901_09330) uvrC 1969370..1971202 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JR901_RS09335 (JR901_09335) pgsA 1971259..1971807 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JR901_RS09355 (JR901_09355) yecA 1972456..1973121 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=474884 JR901_RS09325 WP_000611335.1 1968717..1969373(+) (letA) [Escherichia coli strain 88COLEC]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=474884 JR901_RS09325 WP_000611335.1 1968717..1969373(+) (letA) [Escherichia coli strain 88COLEC]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAAGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486