Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JR895_RS09160 Genome accession   NZ_CP070902
Coordinates   1921399..1922055 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 99COLEC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916399..1927055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JR895_RS09130 (JR895_09130) dcyD 1917278..1918264 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JR895_RS09135 (JR895_09135) tcyL 1918279..1918947 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JR895_RS09140 (JR895_09140) tcyN 1918944..1919696 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JR895_RS09145 (JR895_09145) sdiA 1919926..1920648 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  JR895_RS09150 (JR895_09150) yecF 1920716..1920940 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JR895_RS09155 (JR895_09155) yecU 1920927..1921103 (-) 177 WP_000590344.1 protein YecU -
  JR895_RS24205 - 1921141..1921257 (-) 117 Protein_1814 transcriptional regulator -
  JR895_RS09160 (JR895_09160) letA 1921399..1922055 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JR895_RS09165 (JR895_09165) uvrC 1922052..1923884 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JR895_RS09170 (JR895_09170) pgsA 1923941..1924489 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JR895_RS09190 (JR895_09190) - 1925184..1925924 (-) 741 WP_000440335.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=474803 JR895_RS09160 WP_000611335.1 1921399..1922055(+) (letA) [Escherichia coli strain 99COLEC]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=474803 JR895_RS09160 WP_000611335.1 1921399..1922055(+) (letA) [Escherichia coli strain 99COLEC]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486