Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JW305_RS14310 Genome accession   NZ_CP070593
Coordinates   2606430..2607086 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ESC53083     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2601430..2612086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JW305_RS14270 (JW305_14270) - 2601772..2601954 (+) 183 WP_000916334.1 hypothetical protein -
  JW305_RS14275 (JW305_14275) - 2602164..2602427 (+) 264 WP_000833838.1 DUF4224 domain-containing protein -
  JW305_RS14280 (JW305_14280) - 2602396..2603412 (+) 1017 WP_001531780.1 tyrosine-type recombinase/integrase -
  JW305_RS14300 (JW305_14300) pgsA 2603996..2604544 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JW305_RS14305 (JW305_14305) uvrC 2604601..2606433 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JW305_RS14310 (JW305_14310) letA 2606430..2607086 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JW305_RS14315 (JW305_14315) yecU 2607382..2607558 (+) 177 WP_001307856.1 protein YecU -
  JW305_RS14320 (JW305_14320) yecF 2607545..2607769 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JW305_RS14325 (JW305_14325) sdiA 2607837..2608559 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  JW305_RS14330 (JW305_14330) tcyN 2608789..2609541 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JW305_RS14335 (JW305_14335) tcyL 2609538..2610206 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JW305_RS14340 (JW305_14340) dcyD 2610221..2611207 (-) 987 WP_001128232.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=474562 JW305_RS14310 WP_000611328.1 2606430..2607086(-) (letA) [Escherichia coli strain ESC53083]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=474562 JW305_RS14310 WP_000611328.1 2606430..2607086(-) (letA) [Escherichia coli strain ESC53083]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482