Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I653_RS06740 Genome accession   NC_020832
Coordinates   1321168..1322526 (-) Length   452 a.a.
NCBI ID   WP_015483137.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis str. BAB-1     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1316168..1327526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I653_RS06725 (I653_06590) mhqA 1316332..1317282 (+) 951 WP_015383451.1 ring-cleaving dioxygenase -
  I653_RS20955 - 1317384..1317491 (+) 108 Protein_1313 hypothetical protein -
  I653_RS06730 (I653_06595) ykcB 1317499..1319667 (+) 2169 WP_015383452.1 glycosyltransferase family 39 protein -
  I653_RS06735 (I653_06600) gtcC 1319679..1320650 (+) 972 WP_015483135.1 glycosyltransferase family 2 protein -
  I653_RS06740 (I653_06610) htrA 1321168..1322526 (-) 1359 WP_015483137.1 serine protease HtrA Regulator
  I653_RS06745 (I653_06615) proG 1322695..1323513 (+) 819 WP_015483138.1 pyrroline-5-carboxylate reductase ProG -
  I653_RS06750 (I653_06620) dppA 1323642..1324466 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  I653_RS06755 (I653_06625) dppB 1324483..1325409 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  I653_RS06760 (I653_06630) dppC 1325415..1326377 (+) 963 WP_014476568.1 dipeptide ABC transporter permease DppC -
  I653_RS06765 (I653_06635) dppD 1326382..1327389 (+) 1008 WP_015383458.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 48005.16 Da        Isoelectric Point: 4.5990

>NTDB_id=47453 I653_RS06740 WP_015483137.1 1321168..1322526(-) (htrA) [Bacillus subtilis subsp. subtilis str. BAB-1]
MDNYRDENRTKGIENEVFLTKENDQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLSDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTES
GSGSGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGET
VIAIGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGI
GFAIPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIII
GLKGKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=47453 I653_RS06740 WP_015483137.1 1321168..1322526(-) (htrA) [Bacillus subtilis subsp. subtilis str. BAB-1]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTATTGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCGC
CTCCTACTCAGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTTGCCCTTGGCATCTATACGTTTACACCGCTTAGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCATCAAGCTC
AAGCAGCTCATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCG
GTATTACAAATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGC
GGTTCAGGGTCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGC
ATCATCACTGAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAG
CCGTCCTCCAAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTCAGAACAGGCGAGACC
GTTATTGCGATTGGGGATCCGCTTGGAAAAGATCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAAC
GGTTTCAATGTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACTGACGCAGCAATTAACCCCGGTAACAGCG
GCGGTCCTTTGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGTATC
GGATTTGCCATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAACTGCTGTCAAAAGGTCAAATTGAACGTCCATATAT
CGGTGTCAGCATGCTTGATCTAGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGA
ATAAAGGTGTTTACATCCGTGAAGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCAGAGGATATTATCATC
GGCCTAAAAGGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGATACCGT
TGAAGTGAAAATTCTCAGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(163-307)

PDZ domain (PDZ_2)

(345-444)

Peptidase family M50 (Peptidase_M50)

(369-451)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

40.741

89.602

0.365
  htrA Streptococcus pneumoniae D39

40.741

89.602

0.365
  htrA Streptococcus pneumoniae R6

40.741

89.602

0.365
  htrA Streptococcus pneumoniae TIGR4

40.741

89.602

0.365

Multiple sequence alignment