Detailed information NTG0474438

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: JWY35_RS07680
• Genome accession: NZ_CP070485
• Coordinates: 1448669..1450768 (-)
• Length: 699 a.a.
• NCBI ID: WP_017695065.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain JNFE1126
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1443669..1455768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JWY35_RS07650 (JWY35_07570)	spo0E	1443727..1443984 (+)	258	WP_003218598.1	aspartyl-phosphate phosphatase Spo0E	-
JWY35_RS07655 (JWY35_07575)	-	1444070..1444500 (+)	431	Protein_1446	hypothetical protein	-
JWY35_RS07660 (JWY35_07580)	kinD	1444528..1446048 (-)	1521	WP_031600444.1	sporulation kinase KinD	-
JWY35_RS07665 (JWY35_07585)	mhqR	1446241..1446678 (+)	438	WP_003232475.1	MarR family transcriptional regulator MhqR	-
JWY35_RS07670 (JWY35_07590)	motB	1446718..1447500 (-)	783	WP_014479633.1	flagellar motor protein MotB	-
JWY35_RS07675 (JWY35_07595)	motA	1447475..1448284 (-)	810	WP_014479634.1	flagellar motor stator protein MotA	-
JWY35_RS07680 (JWY35_07600)	clpE	1448669..1450768 (-)	2100	WP_017695065.1	ATP-dependent protease ATP-binding subunit ClpE	Regulator
JWY35_RS07685 (JWY35_07605)	-	1451136..1452179 (+)	1044	WP_014479636.1	hypothetical protein	-
JWY35_RS07690 (JWY35_07610)	queC	1452492..1453151 (+)	660	WP_014479637.1	7-cyano-7-deazaguanine synthase QueC	-
JWY35_RS07695 (JWY35_07615)	queD	1453144..1453593 (+)	450	WP_003232462.1	6-carboxytetrahydropterin synthase QueD	-
JWY35_RS07700 (JWY35_07620)	queE	1453586..1454317 (+)	732	WP_014479638.1	7-carboxy-7-deazaguanine synthase QueE	-
JWY35_RS07705 (JWY35_07625)	queF	1454335..1454832 (+)	498	WP_003218613.1	preQ(1) synthase	-
JWY35_RS07710 (JWY35_07630)	ykvR	1455153..1455443 (+)	291	WP_014479639.1	YkvR family protein	-
JWY35_RS07715 (JWY35_07635)	ykvS	1455565..1455750 (-)	186	WP_003232446.1	YkvS family protein	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77805.88 Da
• Isoelectric Point: 5.1326

>NTDB_id=474438 JWY35_RS07680 WP_017695065.1 1448669..1450768(-) (clpE) [Bacillus subtilis strain JNFE1126]
MRCQHCHQNEATIRLNMQINSVHKQMVLCETCYNELTRKPSMSMGPQSFGFPFEQAFQPKEKSAAKQSGKKGLLDELAQN
ITNGAKAGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVA
NTGIRGQFEERMKQLITELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAAL
ERRFQPVMVQEPSIEQAILILQGIKDKYEAYHGVTFSDEAIKACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLLIDELN
DEDAAERLTAIEAEKTKALEEENYELAAKLRDEELALEKKLNSSSAHTAVTVEAEHIQEIVEQKTGIPVGKLQADEQTKM
KELEAKLHERVIGQEAAVQKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKTLADELFGTKDAIIRLDMSEYME
KHAVSKIIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGAGEKQTKVGFQSDDSVIEEQTLIDSLSMFFKPEFLNRFDSIIEFRSLEKEHLVKIVSLLLGELEETLAERGISLNVTD
EAKEKIAELGYHPSFGARPLRRTIQEWVEDEMTDLLLDNGEITSFHVILEDDKIKVQAK

Nucleotide

• Length: 2100 bp

>NTDB_id=474438 JWY35_RS07680 WP_017695065.1 1448669..1450768(-) (clpE) [Bacillus subtilis strain JNFE1126]
ATGCGTTGTCAACATTGTCATCAAAACGAGGCGACGATTCGCCTTAACATGCAAATAAATTCCGTTCATAAACAGATGGT
TCTTTGTGAAACTTGCTATAACGAACTGACCCGTAAACCTTCAATGAGTATGGGTCCTCAATCTTTCGGATTTCCGTTTG
AACAGGCATTCCAGCCGAAAGAAAAGAGCGCAGCAAAACAAAGCGGAAAAAAAGGGCTGCTTGATGAGCTGGCTCAAAAT
ATTACAAACGGTGCAAAAGCCGGTCTCATTGACCCCGTCATCGGCCGTGATGATGAAGTGGCGCGAGTGATCGAAATTCT
AAACCGCCGGAACAAAAACAATCCGGTTCTTATTGGTGAGCCGGGTGTAGGGAAAACTGCCATCGCTGAAGGGCTCGCTT
TAAAAATTGCTGAAGGTGATGTTCCAAACAAACTGAAAAACAAAGAGCTATATTTGCTTGATGTTGCATCCCTTGTTGCA
AACACAGGGATCAGAGGCCAATTTGAGGAGAGAATGAAACAGCTGATCACTGAGCTGAAGGAACGAAAAAATGTCATTCT
GTTCATTGATGAAATTCACCTTCTCGTCGGCGCAGGCTCTGCAGAAGGATCAATGGACGCCGGCAACATTCTCAAACCGG
CCCTAGCCAGAGGCGAACTGCAAGTCATTGGTGCGACAACACTGAAAGAATATCGTCAAATCGAAAAAGATGCCGCGCTG
GAAAGACGTTTTCAGCCTGTCATGGTGCAGGAGCCTTCAATTGAACAGGCTATCCTCATTCTGCAAGGGATTAAAGACAA
ATACGAGGCATACCATGGCGTAACATTCAGTGATGAAGCAATCAAAGCATGTGTCACTTTATCATCCCGCTACATTCAGG
ACAGACACCTGCCGGATAAAGCAATTGATTTATTAGATGAAGCAGGTTCAAAAGCCAACCTGTTAATTGATGAACTGAAT
GATGAGGATGCCGCTGAACGCTTAACTGCAATTGAAGCCGAAAAAACAAAAGCCCTGGAAGAAGAAAATTACGAACTTGC
GGCAAAACTCCGTGATGAAGAACTCGCATTGGAGAAAAAACTGAACAGCTCCTCCGCTCATACCGCTGTCACTGTGGAAG
CTGAGCACATTCAGGAAATTGTTGAACAAAAAACAGGCATCCCTGTCGGCAAACTGCAGGCAGACGAACAAACGAAAATG
AAAGAACTCGAAGCAAAACTTCATGAACGCGTGATTGGACAAGAAGCCGCTGTTCAAAAAGTGGCAAAGGCGGTAAGACG
AAGCCGCGCCGGTTTAAAATCCAAAAACAGACCAGTCGGCTCCTTCCTCTTCGTCGGTCCTACCGGCGTAGGGAAAACAG
AGCTTTCTAAAACACTGGCAGATGAATTATTCGGCACAAAAGACGCTATTATCCGACTCGATATGAGCGAATACATGGAG
AAACACGCCGTATCTAAAATTATCGGTTCACCGCCTGGATATGTCGGCCATGAGGAAGCTGGACAATTAACTGAGAAAGT
GCGCCGCAATCCTTACAGCATTGTGTTGCTGGATGAGATTGAAAAAGCACACCCAGACGTTCAGCATATGTTCCTGCAAA
TTATGGAGGATGGCCGTCTGACAGACAGCCAAGGCAGAACTGTAAGCTTCAAAGACACAGTGATCATCATGACAAGTAAT
GCGGGTGCTGGTGAGAAACAAACGAAAGTCGGTTTCCAATCAGATGACAGTGTCATCGAAGAACAAACATTGATTGATTC
ACTGAGCATGTTCTTTAAACCTGAGTTCCTCAACCGTTTTGACAGCATTATTGAGTTCCGCTCATTGGAAAAAGAACATC
TTGTCAAAATCGTCAGCCTTCTTCTTGGAGAACTTGAAGAAACATTGGCTGAACGGGGCATTAGCTTGAATGTGACAGAT
GAAGCGAAAGAAAAAATCGCTGAGCTGGGCTACCACCCTTCATTCGGTGCACGTCCGCTTAGAAGAACCATCCAAGAATG
GGTTGAGGATGAAATGACCGATCTGCTGCTTGATAATGGCGAGATCACAAGTTTTCACGTGATTTTAGAAGATGATAAAA
TCAAAGTGCAAGCGAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (253-352)

• AAA domain (Cdc48 subfamily) (AAA_2) (437-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-247)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (609-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	56.528	100	0.601
clpC	Lactococcus lactis subsp. cremoris KW2	56.284	100	0.589
clpE	Streptococcus pneumoniae TIGR4	54.924	100	0.567
clpE	Streptococcus pneumoniae Rx1	54.924	100	0.567
clpE	Streptococcus pneumoniae D39	54.924	100	0.567
clpE	Streptococcus pneumoniae R6	54.924	100	0.567
clpC	Bacillus subtilis subsp. subtilis str. 168	54.016	90.844	0.491
clpC	Streptococcus pneumoniae Rx1	45.732	93.848	0.429
clpC	Streptococcus pneumoniae D39	45.732	93.848	0.429
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.847	89.7	0.429
clpC	Streptococcus thermophilus LMD-9	45.427	93.848	0.426
clpC	Streptococcus thermophilus LMG 18311	44.97	93.848	0.422
clpC	Streptococcus pneumoniae TIGR4	46.85	88.555	0.415
clpC	Streptococcus mutans UA159	46.216	88.841	0.411
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	42.079	86.695	0.365