Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H6X75_RS01945 Genome accession   NZ_CP060156
Coordinates   369814..370503 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 364814..375503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS01920 (H6X75_01890) gpsB 364923..365252 (+) 330 WP_000146522.1 cell division regulator GpsB -
  H6X75_RS01930 (H6X75_01900) - 365738..366895 (+) 1158 WP_000711395.1 class I SAM-dependent RNA methyltransferase -
  H6X75_RS01935 (H6X75_01905) mapZ 366908..368302 (+) 1395 WP_000039279.1 mid-cell-anchored protein MapZ -
  H6X75_RS01940 (H6X75_01910) gndA 368378..369802 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  H6X75_RS01945 (H6X75_01915) covR 369814..370503 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  H6X75_RS01950 (H6X75_01920) cbpC 370601..371620 (+) 1020 WP_000771096.1 choline-binding protein CbpC -
  H6X75_RS01955 (H6X75_01925) - 371738..372970 (-) 1233 WP_000765667.1 MFS transporter -
  H6X75_RS01960 (H6X75_01930) - 372981..373433 (-) 453 WP_000499617.1 hypothetical protein -
  H6X75_RS01965 (H6X75_01935) - 373501..373889 (-) 389 Protein_387 lanthionine synthetase LanC family protein -
  H6X75_RS11215 - 374501..374830 (+) 330 WP_000196976.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=474135 H6X75_RS01945 WP_000518008.1 369814..370503(+) (covR) [Streptococcus pneumoniae strain PZ900700608]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=474135 H6X75_RS01945 WP_000518008.1 369814..370503(+) (covR) [Streptococcus pneumoniae strain PZ900700608]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467