Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LLUL021_RS04900 Genome accession   NZ_CP070263
Coordinates   970851..971480 (+) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis subsp. lactis strain UL021     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 965851..976480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUL021_RS04870 (LLUL021_04850) - 966133..967332 (+) 1200 WP_003131394.1 FtsW/RodA/SpoVE family cell cycle protein -
  LLUL021_RS04875 (LLUL021_14120) - 967363..967917 (+) 555 WP_249351744.1 LCP family protein -
  LLUL021_RS04880 (LLUL021_14125) - 967978..968661 (+) 684 WP_003131396.1 LCP family protein -
  LLUL021_RS04885 (LLUL021_04860) rpsN 968764..969033 (+) 270 WP_003131398.1 30S ribosomal protein S14 -
  LLUL021_RS04890 (LLUL021_04865) liaF 969199..969828 (+) 630 WP_003131399.1 cell wall-active antibiotics response protein LiaF -
  LLUL021_RS04895 (LLUL021_04870) - 969825..970823 (+) 999 WP_012897540.1 sensor histidine kinase -
  LLUL021_RS04900 (LLUL021_04875) vraR 970851..971480 (+) 630 WP_003131402.1 response regulator transcription factor Regulator
  LLUL021_RS04905 (LLUL021_04880) - 971551..972357 (+) 807 WP_003131403.1 Cof-type HAD-IIB family hydrolase -
  LLUL021_RS04910 (LLUL021_04885) - 972460..973050 (+) 591 WP_003131404.1 peptidylprolyl isomerase -
  LLUL021_RS04915 (LLUL021_04890) - 973052..973483 (+) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  LLUL021_RS04920 (LLUL021_04895) - 973480..974085 (+) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  LLUL021_RS04925 (LLUL021_04900) - 974305..975549 (+) 1245 WP_137016189.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=473795 LLUL021_RS04900 WP_003131402.1 970851..971480(+) (vraR) [Lactococcus lactis subsp. lactis strain UL021]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=473795 LLUL021_RS04900 WP_003131402.1 970851..971480(+) (vraR) [Lactococcus lactis subsp. lactis strain UL021]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACTCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416