Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JTF63_RS08795 Genome accession   NZ_CP070232
Coordinates   1850083..1850739 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 10R     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1845083..1855739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JTF63_RS08765 (JTF63_08765) dcyD 1845962..1846948 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JTF63_RS08770 (JTF63_08770) tcyL 1846963..1847631 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JTF63_RS08775 (JTF63_08775) tcyN 1847628..1848380 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JTF63_RS08780 (JTF63_08780) sdiA 1848610..1849332 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  JTF63_RS08785 (JTF63_08785) yecF 1849400..1849624 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JTF63_RS08790 (JTF63_08790) yecU 1849611..1849787 (-) 177 WP_000590344.1 protein YecU -
  JTF63_RS22720 - 1849825..1849941 (-) 117 WP_001302039.1 hypothetical protein -
  JTF63_RS08795 (JTF63_08795) letA 1850083..1850739 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JTF63_RS08800 (JTF63_08800) uvrC 1850736..1852568 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JTF63_RS08805 (JTF63_08805) pgsA 1852625..1853173 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JTF63_RS08825 (JTF63_08825) - 1853755..1854762 (-) 1008 WP_039268413.1 tyrosine-type recombinase/integrase -
  JTF63_RS08830 (JTF63_08830) - 1854759..1855625 (-) 867 WP_052424691.1 BRCT domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=473724 JTF63_RS08795 WP_000611328.1 1850083..1850739(+) (letA) [Escherichia coli strain 10R]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=473724 JTF63_RS08795 WP_000611328.1 1850083..1850739(+) (letA) [Escherichia coli strain 10R]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482