Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JTC67_RS00425 Genome accession   NZ_CP070229
Coordinates   76133..76789 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 71133..81789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JTC67_RS00395 (JTC67_00390) dcyD 72012..72998 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  JTC67_RS00400 (JTC67_00395) tcyL 73013..73681 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JTC67_RS00405 (JTC67_00400) tcyN 73678..74430 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JTC67_RS00410 (JTC67_00405) sdiA 74660..75382 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  JTC67_RS00415 (JTC67_00410) yecF 75450..75674 (-) 225 WP_062859938.1 DUF2594 family protein YecF -
  JTC67_RS00420 (JTC67_00415) yecU 75661..75837 (-) 177 WP_001307856.1 protein YecU -
  JTC67_RS00425 (JTC67_00420) letA 76133..76789 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JTC67_RS00430 (JTC67_00425) uvrC 76786..78618 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JTC67_RS00435 (JTC67_00430) pgsA 78675..79223 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JTC67_RS00455 (JTC67_00450) yecA 79873..80538 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=473611 JTC67_RS00425 WP_000611328.1 76133..76789(+) (letA) [Escherichia coli strain EC12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=473611 JTC67_RS00425 WP_000611328.1 76133..76789(+) (letA) [Escherichia coli strain EC12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482