Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   H4989_RS00580 Genome accession   NZ_CP059970
Coordinates   105091..105864 (+) Length   257 a.a.
NCBI ID   WP_002918419.1    Uniprot ID   -
Organism   Campylobacter jejuni strain C57     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 38739..111888 105091..105864 within 0


Gene organization within MGE regions


Location: 38739..111888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4989_RS00245 (H4989_00245) - 39106..39438 (+) 333 WP_002853247.1 membrane protein -
  H4989_RS00250 (H4989_00250) apt 39435..39983 (+) 549 WP_002859569.1 adenine phosphoribosyltransferase -
  H4989_RS00255 (H4989_00255) - 40002..40598 (+) 597 WP_002854047.1 DedA family protein -
  H4989_RS00260 (H4989_00260) - 40595..42046 (+) 1452 WP_002876027.1 leucyl aminopeptidase -
  H4989_RS00265 (H4989_00265) ychF 42043..43146 (+) 1104 WP_002853275.1 redox-regulated ATPase YchF -
  H4989_RS00270 (H4989_00270) argH 43168..44550 (-) 1383 WP_002859571.1 argininosuccinate lyase -
  H4989_RS00275 (H4989_00275) pckA 44560..46134 (-) 1575 WP_002859572.1 phosphoenolpyruvate carboxykinase (ATP) -
  H4989_RS00280 (H4989_00280) pycB 46147..47946 (-) 1800 WP_002859573.1 biotin/lipoyl-containing protein -
  H4989_RS00285 (H4989_00285) - 47978..49318 (-) 1341 WP_011049815.1 sodium-dependent transporter -
  H4989_RS00290 (H4989_00290) - 49331..50665 (-) 1335 WP_002858451.1 sodium-dependent transporter -
  H4989_RS00295 (H4989_00295) - 50693..51268 (-) 576 WP_182579590.1 NTPase -
  H4989_RS00300 (H4989_00300) - 51297..51578 (-) 282 WP_002809140.1 hypothetical protein -
  H4989_RS00305 (H4989_00305) - 51772..52323 (+) 552 WP_002779777.1 hypothetical protein -
  H4989_RS00310 (H4989_00310) mobP1 52323..53711 (+) 1389 WP_002790553.1 MobP1 family relaxase -
  H4989_RS00315 (H4989_00315) - 53803..54474 (+) 672 WP_224327015.1 N-acetyltransferase -
  H4989_RS00320 (H4989_00320) - 54449..55060 (-) 612 WP_031263757.1 NYN domain-containing protein -
  H4989_RS00325 (H4989_00325) - 55314..61112 (-) 5799 WP_002839415.1 SNF2-related protein -
  H4989_RS00330 (H4989_00330) - 61159..61425 (-) 267 WP_002804244.1 hypothetical protein -
  H4989_RS00335 (H4989_00335) - 61428..61988 (-) 561 WP_002790730.1 hypothetical protein -
  H4989_RS00340 (H4989_00340) - 62047..62313 (-) 267 WP_002779704.1 hypothetical protein -
  H4989_RS00345 (H4989_00345) - 62318..62593 (-) 276 WP_002804241.1 hypothetical protein -
  H4989_RS00350 (H4989_00350) - 62667..63905 (-) 1239 WP_002784330.1 RNA-guided endonuclease TnpB family protein -
  H4989_RS00355 (H4989_00355) tnpA 63892..64365 (-) 474 WP_002817206.1 IS200/IS605 family transposase -
  H4989_RS00360 (H4989_00360) aph(3')-IIIa 64656..65450 (-) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  H4989_RS00365 (H4989_00365) sat4 65543..66085 (-) 543 WP_057044112.1 streptothricin N-acetyltransferase Sat4 -
  H4989_RS00370 (H4989_00370) - 66082..66633 (-) 552 Protein_73 aminoglycoside 6-adenylyltransferase -
  H4989_RS09255 - 66643..66702 (-) 60 Protein_74 hypothetical protein -
  H4989_RS00375 (H4989_00375) - 66729..67766 (-) 1038 WP_032491276.1 IS1595-like element ISCco2 family transposase -
  H4989_RS00380 (H4989_00380) - 68095..68268 (-) 174 WP_002779755.1 cysteine-rich KTR domain-containing protein -
  H4989_RS00385 (H4989_00385) tet(O) 68320..70239 (-) 1920 WP_002909882.1 tetracycline resistance ribosomal protection protein Tet(O) -
  H4989_RS00390 (H4989_00390) - 70598..70777 (-) 180 WP_002779751.1 hypothetical protein -
  H4989_RS00395 (H4989_00395) - 70796..71497 (-) 702 WP_002865633.1 hypothetical protein -
  H4989_RS00400 (H4989_00400) - 72249..73115 (-) 867 WP_001255868.1 aminoglycoside 6-adenylyltransferase AadE -
  H4989_RS00405 (H4989_00405) - 73291..73836 (-) 546 WP_057044102.1 AAA family ATPase -
  H4989_RS00410 (H4989_00410) - 73988..74686 (-) 699 WP_004292762.1 GNAT family N-acetyltransferase -
  H4989_RS00415 (H4989_00415) - 74707..75507 (-) 801 WP_057044114.1 helix-turn-helix transcriptional regulator -
  H4989_RS00420 (H4989_00420) - 75842..76255 (+) 414 WP_007215983.1 cysteine-rich VLP domain-containing protein -
  H4989_RS00425 (H4989_00425) - 76366..76761 (+) 396 WP_074485792.1 replication initiator protein A -
  H4989_RS00430 (H4989_00430) mobV 76944..77885 (+) 942 WP_057044104.1 MobV family relaxase -
  H4989_RS00435 (H4989_00435) - 77869..78084 (+) 216 WP_057044105.1 hypothetical protein -
  H4989_RS00440 (H4989_00440) - 78179..79690 (+) 1512 WP_007215987.1 recombinase family protein -
  H4989_RS00445 (H4989_00445) - 79717..80142 (-) 426 WP_057044106.1 hypothetical protein -
  H4989_RS00450 (H4989_00450) - 80248..82440 (-) 2193 WP_057044107.1 DNA topoisomerase 3 -
  H4989_RS00455 (H4989_00455) - 82703..83323 (-) 621 WP_002809107.1 hypothetical protein -
  H4989_RS00460 (H4989_00460) - 83394..84191 (-) 798 WP_002809110.1 hypothetical protein -
  H4989_RS00465 (H4989_00465) - 84194..84958 (-) 765 WP_002809111.1 TrbM/KikA/MpfK family conjugal transfer protein -
  H4989_RS00470 (H4989_00470) - 84970..85407 (-) 438 WP_002869582.1 cag pathogenicity island Cag12 family protein -
  H4989_RS00475 (H4989_00475) - 85388..87199 (-) 1812 WP_002869581.1 type IV secretory system conjugative DNA transfer family protein -
  H4989_RS00480 (H4989_00480) virB11 87200..88192 (-) 993 WP_002826431.1 P-type DNA transfer ATPase VirB11 -
  H4989_RS00485 (H4989_00485) virB10 88173..89348 (-) 1176 WP_002826433.1 type IV secretion system protein VirB10 -
  H4989_RS00490 (H4989_00490) virB9 89375..90262 (-) 888 WP_002809121.1 P-type conjugative transfer protein VirB9 -
  H4989_RS00495 (H4989_00495) - 90259..90921 (-) 663 WP_002809287.1 type IV secretion system protein -
  H4989_RS00500 (H4989_00500) - 90911..91078 (-) 168 WP_002809290.1 hypothetical protein -
  H4989_RS00505 (H4989_00505) - 91068..92066 (-) 999 WP_019109194.1 type IV secretion system protein -
  H4989_RS00510 (H4989_00510) - 92063..93034 (-) 972 WP_019109193.1 type IV secretion system protein -
  H4989_RS00515 (H4989_00515) - 93038..93313 (-) 276 WP_002779630.1 hypothetical protein -
  H4989_RS00520 (H4989_00520) - 93329..93754 (-) 426 WP_002809063.1 single-stranded DNA-binding protein -
  H4989_RS00525 (H4989_00525) - 93788..94354 (-) 567 WP_002809061.1 hypothetical protein -
  H4989_RS00530 (H4989_00530) - 94351..94908 (-) 558 WP_057044108.1 Rha family transcriptional regulator -
  H4989_RS00535 (H4989_00535) - 94919..97687 (-) 2769 WP_057044109.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  H4989_RS00540 (H4989_00540) - 97706..97969 (-) 264 WP_002869705.1 TrbC/VirB2 family protein -
  H4989_RS00545 (H4989_00545) - 98139..98462 (+) 324 WP_002809052.1 hypothetical protein -
  H4989_RS00550 (H4989_00550) vapD 98453..98830 (+) 378 WP_002809051.1 virulence-associated protein VapD -
  H4989_RS00555 (H4989_00555) - 98827..99441 (+) 615 WP_002809050.1 recombinase family protein -
  H4989_RS00560 (H4989_00560) holA 99982..100947 (-) 966 WP_032593411.1 DNA polymerase III subunit delta -
  H4989_RS00565 (H4989_00565) - 100940..102874 (-) 1935 WP_182101490.1 ribonuclease R family protein -
  H4989_RS00570 (H4989_00570) ilvC 102993..104015 (+) 1023 WP_032581040.1 ketol-acid reductoisomerase -
  H4989_RS00575 (H4989_00575) - 104019..105101 (+) 1083 WP_146314506.1 divergent polysaccharide deacetylase family protein -
  H4989_RS00580 (H4989_00580) dprA 105091..105864 (+) 774 WP_002918419.1 DNA-processing protein DprA Machinery gene
  H4989_RS00585 (H4989_00585) ruvX 105861..106244 (+) 384 WP_002918422.1 Holliday junction resolvase RuvX -
  H4989_RS00590 (H4989_00590) - 106273..107112 (+) 840 WP_002866496.1 RsmB/NOP family class I SAM-dependent RNA methyltransferase -
  H4989_RS00595 (H4989_00595) msrA 107288..107785 (-) 498 WP_002852283.1 peptide-methionine (S)-S-oxide reductase MsrA -
  H4989_RS00600 (H4989_00600) ppa 107827..108345 (-) 519 WP_002867724.1 inorganic diphosphatase -
  H4989_RS00605 (H4989_00605) adk 108355..108933 (-) 579 WP_002859580.1 adenylate kinase -
  H4989_RS00610 (H4989_00610) aspS 108930..110681 (-) 1752 WP_182101491.1 aspartate--tRNA ligase -
  H4989_RS00615 (H4989_00615) - 110772..111632 (+) 861 WP_002908825.1 NAD(+) kinase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28919.74 Da        Isoelectric Point: 7.7211

>NTDB_id=472908 H4989_RS00580 WP_002918419.1 105091..105864(+) (dprA) [Campylobacter jejuni strain C57]
MASEILPDEFLELFKDLKKPPKKLHYKGNLSLLKQDKIAIIGSRRMSVYTKNRVFSLASMLKNAHLCVVSGGALGVDITA
SMAAMPNTIGIFANGLDQIYPRTNEKIIKQIYENALALSEYEDDYLPKNYDFLLRNRLVIALSKAVVVAQADIKSGSMQS
AKLALELNKPLYVLPQRLEESTGTNFLLKENKAKLICDFKEFVSEFASIDMNQDEFLEFCKKGVSVDEALKIYGQKVYEY
ELEGKISIEGLFIRVLA

Nucleotide


Download         Length: 774 bp        

>NTDB_id=472908 H4989_RS00580 WP_002918419.1 105091..105864(+) (dprA) [Campylobacter jejuni strain C57]
ATGGCAAGTGAAATTTTGCCTGATGAGTTTTTAGAACTTTTTAAAGATTTAAAAAAGCCTCCTAAAAAATTACACTATAA
AGGAAATTTATCTTTATTAAAACAAGATAAAATCGCTATTATAGGTTCAAGGCGTATGAGTGTTTATACGAAAAATCGTG
TTTTTTCCTTAGCGAGTATGCTTAAAAATGCTCATCTTTGTGTGGTAAGTGGCGGTGCTTTGGGTGTGGATATCACCGCA
AGTATGGCAGCTATGCCAAATACTATAGGTATTTTTGCCAATGGTTTAGATCAAATTTATCCAAGAACTAATGAAAAAAT
CATTAAACAAATTTATGAAAATGCTTTGGCTTTAAGCGAATACGAAGATGATTATTTGCCAAAAAATTATGACTTTTTAC
TAAGAAATCGTTTGGTTATTGCTTTAAGTAAGGCCGTTGTAGTTGCACAAGCAGATATAAAAAGTGGTTCTATGCAAAGT
GCAAAACTTGCTTTAGAACTCAATAAGCCTTTATATGTTTTACCGCAAAGACTAGAAGAAAGCACAGGAACTAATTTTCT
TTTAAAGGAAAATAAAGCAAAGTTAATTTGTGATTTTAAAGAATTTGTAAGTGAGTTTGCAAGTATAGATATGAATCAAG
ATGAATTTTTAGAGTTTTGTAAAAAAGGTGTGAGTGTTGATGAGGCTTTAAAAATTTATGGACAAAAAGTTTATGAATAT
GAACTTGAGGGAAAAATTTCCATAGAAGGGCTTTTTATAAGGGTTTTAGCATGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(9-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

98.444

100

0.984
  dprA Helicobacter pylori 26695

49.167

93.385

0.459