Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   H4K32_RS12835 Genome accession   NZ_CP059855
Coordinates   2485990..2486634 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain Pm9     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2480990..2491634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4K32_RS12810 - 2481432..2481773 (-) 342 WP_014305721.1 hypothetical protein -
  H4K32_RS12815 degQ 2482239..2482379 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  H4K32_RS12820 - 2482531..2483442 (+) 912 WP_014305720.1 polyprenyl synthetase family protein -
  H4K32_RS12825 comX 2483442..2483606 (+) 165 WP_007613432.1 competence pheromone ComX -
  H4K32_RS12830 comP 2483618..2485909 (+) 2292 WP_015387784.1 histidine kinase Regulator
  H4K32_RS12835 comA 2485990..2486634 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  H4K32_RS12840 - 2486656..2487039 (+) 384 WP_003152054.1 hotdog fold thioesterase -
  H4K32_RS12845 mnhG 2487079..2487453 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  H4K32_RS12850 - 2487437..2487721 (-) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  H4K32_RS12855 - 2487721..2488197 (-) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  H4K32_RS12860 - 2488203..2489684 (-) 1482 WP_043867375.1 Na+/H+ antiporter subunit D -
  H4K32_RS12865 - 2489677..2490018 (-) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  H4K32_RS12870 - 2490018..2490449 (-) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=472302 H4K32_RS12835 WP_003152052.1 2485990..2486634(+) (comA) [Bacillus velezensis strain Pm9]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=472302 H4K32_RS12835 WP_003152052.1 2485990..2486634(+) (comA) [Bacillus velezensis strain Pm9]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864