Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K23_RS01605 Genome accession   NZ_CP070041
Coordinates   354519..355175 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1293     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 349519..360175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K23_RS01575 (I6K23_01575) dcyD 350398..351384 (+) 987 Protein_314 D-cysteine desulfhydrase -
  I6K23_RS01580 (I6K23_01580) tcyL 351399..352067 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K23_RS01585 (I6K23_01585) tcyN 352064..352816 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K23_RS01590 (I6K23_01590) sdiA 353046..353768 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6K23_RS01595 (I6K23_01595) yecF 353836..354060 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K23_RS01600 (I6K23_01600) yecU 354047..354223 (-) 177 WP_001304283.1 protein YecU -
  I6K23_RS01605 (I6K23_01605) letA 354519..355175 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K23_RS01610 (I6K23_01610) uvrC 355172..357004 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6K23_RS01615 (I6K23_01615) pgsA 357061..357609 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K23_RS01635 (I6K23_01635) yecA 358258..358923 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=472000 I6K23_RS01605 WP_000611328.1 354519..355175(+) (letA) [Escherichia coli strain FDAARGOS_1293]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=472000 I6K23_RS01605 WP_000611328.1 354519..355175(+) (letA) [Escherichia coli strain FDAARGOS_1293]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482