Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K18_RS18710 Genome accession   NZ_CP070007
Coordinates   3926732..3927388 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1288     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3921732..3932388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K18_RS18680 (I6K18_18680) dcyD 3922611..3923597 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  I6K18_RS18685 (I6K18_18685) tcyL 3923612..3924280 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K18_RS18690 (I6K18_18690) tcyN 3924277..3925029 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K18_RS18695 (I6K18_18695) sdiA 3925259..3925981 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  I6K18_RS18700 (I6K18_18700) yecF 3926049..3926273 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K18_RS18705 (I6K18_18705) yecU 3926260..3926436 (-) 177 WP_000590347.1 protein YecU -
  I6K18_RS18710 (I6K18_18710) letA 3926732..3927388 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K18_RS18715 (I6K18_18715) uvrC 3927385..3929217 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6K18_RS18720 (I6K18_18720) pgsA 3929274..3929822 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K18_RS18740 (I6K18_18740) - 3930808..3931089 (+) 282 WP_001303543.1 hypothetical protein -
  I6K18_RS18745 (I6K18_18745) - 3931278..3931418 (-) 141 WP_000078920.1 Hok/Gef family protein -
  I6K18_RS18750 (I6K18_18750) - 3931609..3931869 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=471900 I6K18_RS18710 WP_000611328.1 3926732..3927388(+) (letA) [Escherichia coli strain FDAARGOS_1288]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=471900 I6K18_RS18710 WP_000611328.1 3926732..3927388(+) (letA) [Escherichia coli strain FDAARGOS_1288]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482