Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K34_RS04430 Genome accession   NZ_CP069990
Coordinates   933399..934055 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1304     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 928399..939055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K34_RS04400 (I6K34_04400) dcyD 929278..930264 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  I6K34_RS04405 (I6K34_04405) tcyL 930279..930947 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K34_RS04410 (I6K34_04410) tcyN 930944..931696 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K34_RS04415 (I6K34_04415) sdiA 931926..932648 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6K34_RS04420 (I6K34_04420) yecF 932716..932940 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K34_RS04425 (I6K34_04425) yecU 932927..933103 (-) 177 WP_001307856.1 protein YecU -
  I6K34_RS04430 (I6K34_04430) letA 933399..934055 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K34_RS04435 (I6K34_04435) uvrC 934052..935884 (+) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  I6K34_RS04440 (I6K34_04440) pgsA 935941..936489 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K34_RS04460 (I6K34_04460) yecA 937139..937804 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=471665 I6K34_RS04430 WP_000611328.1 933399..934055(+) (letA) [Escherichia coli strain FDAARGOS_1304]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=471665 I6K34_RS04430 WP_000611328.1 933399..934055(+) (letA) [Escherichia coli strain FDAARGOS_1304]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482