Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K32_RS08090 Genome accession   NZ_CP069935
Coordinates   1619824..1620480 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain FDAARGOS_1302     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1614824..1625480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K32_RS08060 (I6K32_08055) yecA 1616075..1616740 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  I6K32_RS08080 (I6K32_08075) pgsA 1617390..1617938 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K32_RS08085 (I6K32_08080) uvrC 1617995..1619827 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6K32_RS08090 (I6K32_08085) letA 1619824..1620480 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K32_RS25435 - 1620622..1620693 (+) 72 Protein_1606 transcriptional regulator -
  I6K32_RS08095 (I6K32_08090) yecU 1620776..1620952 (+) 177 WP_001326718.1 protein YecU -
  I6K32_RS08100 (I6K32_08095) yecF 1620939..1621163 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K32_RS08105 (I6K32_08100) sdiA 1621230..1621952 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  I6K32_RS08110 (I6K32_08105) tcyN 1622182..1622934 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K32_RS08115 (I6K32_08110) tcyL 1622931..1623599 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K32_RS08120 (I6K32_08115) dcyD 1623614..1624600 (-) 987 WP_001128222.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=471160 I6K32_RS08090 WP_000611335.1 1619824..1620480(-) (letA) [Escherichia coli strain FDAARGOS_1302]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=471160 I6K32_RS08090 WP_000611335.1 1619824..1620480(-) (letA) [Escherichia coli strain FDAARGOS_1302]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486