Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   I6K87_RS04130 Genome accession   NZ_CP069892
Coordinates   829291..830643 (-) Length   450 a.a.
NCBI ID   WP_003027674.1    Uniprot ID   A0ABD7NEK8
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 824291..835643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS04110 (I6K87_04110) rnc 825946..826644 (-) 699 WP_049534586.1 ribonuclease III -
  I6K87_RS04115 (I6K87_04115) - 827018..827376 (-) 359 Protein_805 YbaN family protein -
  I6K87_RS04120 (I6K87_04120) - 827457..828407 (+) 951 Protein_806 IS30 family transposase -
  I6K87_RS04125 (I6K87_04125) vicX 828485..829288 (-) 804 WP_003027672.1 MBL fold metallo-hydrolase Regulator
  I6K87_RS04130 (I6K87_04130) micB 829291..830643 (-) 1353 WP_003027674.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6K87_RS04135 (I6K87_04135) yycF 830636..831337 (-) 702 WP_059220602.1 response regulator YycF -
  I6K87_RS04140 (I6K87_04140) - 831621..831962 (-) 342 WP_049533028.1 hypothetical protein -
  I6K87_RS04145 (I6K87_04145) - 831989..833302 (-) 1314 WP_022525097.1 glycosyltransferase family 4 protein -
  I6K87_RS04150 (I6K87_04150) - 833304..834302 (-) 999 WP_049533026.1 glycosyltransferase family 4 protein -
  I6K87_RS04155 (I6K87_04155) ccpA 834482..835486 (-) 1005 WP_049533025.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51390.62 Da        Isoelectric Point: 4.6926

>NTDB_id=470975 I6K87_RS04130 WP_003027674.1 829291..830643(-) (micB) [Streptococcus anginosus strain FDAARGOS_1357]
MIDNIRQFVVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=470975 I6K87_RS04130 WP_003027674.1 829291..830643(-) (micB) [Streptococcus anginosus strain FDAARGOS_1357]
ATGATTGATAATATTAGACAATTTGTTGTATCAAAAGATTTTGTATTTGTCTTACTCATTTTAGGATTTATTTTGGTGAT
TACCTTGCTTTCCTTGGAAAACCGACGTGATAATGTTCGTATTCGCCAATTGAATCAAAAAGTGAAAGACTTAATTGCAG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGCCCAGAAATTACGGATATTACTAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGTCTGTCGAGTATTTTATCCTATATGACGGACGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCGACCAAGCAGTTGGGGGTTAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGCTGGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
CTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTTCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCAGTGCTGCATGATACAACGGAGCAGGAAAAAGAGGAACGTGAGCGGAGACTATTTGTTT
CTAATGTCAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAGGGTGCTTTGTCT
GAGCCAGTTGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCTACCAGTCATTTGGATATTGAGCTGACAAATTTTACAGCTTTCATCACCTTTATTTTGA
ATCGTTTTGATAAAATCAGAAGTCAGAATGATGATAAGAAGTACGAAATTATTCGAGATTATCCTATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCTATATCAGATGAGGGCTTAGGGATTCCTAAAA
AAGATTTACCGAAAATTTTTGACCGCTTCTATCGTGTAGACAAAGCAAGAAGTCGTGCACAAGGTGGATCCGGATTAGGT
TTAGCTATTGCTAAGGAAATTATTAAGCAACATCACGGATTTATCTGGGCAAAGAGCGAGTATGGCAAAGGCTCAACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0ABD7NEK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

71.638

90.889

0.651