Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HBNCFIEN_RS12600 Genome accession   NZ_CP059576
Coordinates   2911916..2912575 (-) Length   219 a.a.
NCBI ID   WP_182391424.1    Uniprot ID   A0A7G4RIX8
Organism   Legionella sp. PC997     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2906916..2917575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBNCFIEN_RS12585 (HBNCFIEN_02545) - 2908401..2908967 (-) 567 WP_182393697.1 endopeptidase IV -
  HBNCFIEN_RS12590 (HBNCFIEN_02546) - 2908976..2909689 (-) 714 WP_182391422.1 L,D-transpeptidase -
  HBNCFIEN_RS12595 (HBNCFIEN_02547) uvrC 2909932..2911794 (-) 1863 WP_182391423.1 excinuclease ABC subunit UvrC -
  HBNCFIEN_RS12600 (HBNCFIEN_02548) letA 2911916..2912575 (-) 660 WP_182391424.1 two-component system response regulator LetA Regulator
  HBNCFIEN_RS12605 (HBNCFIEN_02549) phhA 2912659..2913477 (-) 819 WP_182391425.1 phenylalanine 4-monooxygenase -
  HBNCFIEN_RS12610 (HBNCFIEN_02550) - 2913653..2914750 (+) 1098 WP_182391426.1 molybdopterin-binding protein -
  HBNCFIEN_RS12615 (HBNCFIEN_02551) cgtA 2914706..2915731 (-) 1026 WP_182391427.1 Obg family GTPase CgtA -
  HBNCFIEN_RS12620 (HBNCFIEN_02552) rpmA 2915883..2916161 (-) 279 WP_182391428.1 50S ribosomal protein L27 -
  HBNCFIEN_RS12625 (HBNCFIEN_02553) rplU 2916174..2916485 (-) 312 WP_182391429.1 50S ribosomal protein L21 -
  HBNCFIEN_RS12630 (HBNCFIEN_02554) - 2916760..2917425 (+) 666 WP_182391430.1 50S ribosomal protein L25/general stress protein Ctc -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24374.36 Da        Isoelectric Point: 5.0255

>NTDB_id=470918 HBNCFIEN_RS12600 WP_182391424.1 2911916..2912575(-) (letA) [Legionella sp. PC997]
MIKVLIVDDHALVRMGIRRLLEDMSDVEVVADAESGEEALALVKKHSPDVVLLDMKMPGIDGWEVTRRLKKSNPHVKVIA
VTAMCSDLLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQRVAINSLEEVQGSPFDVLSEREMQVMLMI
TSGMNVQEISDRLFLSTKTINGYRYRTFEKLGIKNDVELTYLALKHGIIENPIDLTSED

Nucleotide


Download         Length: 660 bp        

>NTDB_id=470918 HBNCFIEN_RS12600 WP_182391424.1 2911916..2912575(-) (letA) [Legionella sp. PC997]
TTGATTAAAGTACTAATTGTTGATGACCATGCACTGGTTAGAATGGGTATTCGACGATTACTCGAAGATATGTCGGATGT
AGAGGTAGTTGCTGATGCAGAAAGCGGTGAAGAAGCTTTAGCACTGGTAAAAAAACATTCTCCTGACGTGGTCCTTTTAG
ATATGAAAATGCCTGGAATCGATGGCTGGGAAGTAACACGTCGCCTAAAAAAATCAAATCCACATGTTAAGGTTATAGCT
GTAACCGCGATGTGTTCTGATTTGTTACCAACTCGCGTTTTGCAATTAGGAGCTATGGGGTATCTGACTAAAGAATCAGG
TGCTGAAGAAATGGCTGCAGCGATACGTAAAGTGGCCAAAGGCGAAAAGTACCTCAGCGCTGAAATTGCTCAAAGAGTCG
CGATTAATAGCTTGGAAGAAGTACAAGGCTCACCCTTTGATGTATTGTCTGAACGTGAAATGCAAGTGATGTTGATGATT
ACTAGTGGCATGAATGTGCAAGAAATTAGTGATAGGCTTTTTCTTAGCACCAAGACAATTAATGGCTACCGCTATCGAAC
ATTTGAAAAATTAGGCATTAAAAATGATGTAGAGTTGACTTATTTAGCTCTAAAACATGGAATTATAGAAAATCCAATCG
ACTTGACGTCAGAAGATTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-203)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G4RIX8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

88.128

100

0.881
  letA Legionella pneumophila strain ERS1305867

88.128

100

0.881