Detailed information NTG0470914

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: HBNCFIEN_RS10030
• Genome accession: NZ_CP059576
• Coordinates: 2335033..2337768 (+)
• Length: 911 a.a.
• NCBI ID: WP_182393670.1
• Uniprot ID: -
• Organism: Legionella sp. PC997
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2330033..2342768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HBNCFIEN_RS10015 (HBNCFIEN_02023)	-	2330566..2331927 (-)	1362	WP_182393730.1	hypothetical protein	-
HBNCFIEN_RS10020 (HBNCFIEN_02024)	-	2332080..2333342 (-)	1263	WP_182390957.1	serine hydrolase	-
HBNCFIEN_RS10025 (HBNCFIEN_02025)	gltX	2333460..2334875 (-)	1416	WP_182390958.1	glutamate--tRNA ligase	-
HBNCFIEN_RS10030 (HBNCFIEN_02026)	letS	2335033..2337768 (+)	2736	WP_182393670.1	two-component system sensor histidine kinase LetS	Regulator
HBNCFIEN_RS10035 (HBNCFIEN_02027)	-	2337841..2339079 (+)	1239	WP_182390959.1	6-phosphofructokinase	-
HBNCFIEN_RS10040 (HBNCFIEN_02028)	pilA	2339363..2339794 (+)	432	WP_304599254.1	pilin	Machinery gene
HBNCFIEN_RS10045 (HBNCFIEN_02029)	-	2339859..2340188 (+)	330	WP_182390960.1	BolA family transcriptional regulator	-
HBNCFIEN_RS10050 (HBNCFIEN_02030)	-	2340289..2340627 (+)	339	WP_182390961.1	hypothetical protein	-
HBNCFIEN_RS10055 (HBNCFIEN_02031)	-	2340868..2342304 (+)	1437	WP_182390962.1	APC family permease	-
HBNCFIEN_RS10060 (HBNCFIEN_02032)	-	2342360..2342539 (-)	180	WP_182390963.1	Trm112 family protein	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 102907.52 Da
• Isoelectric Point: 7.9154

>NTDB_id=470914 HBNCFIEN_RS10030 WP_182393670.1 2335033..2337768(+) (letS) [Legionella sp. PC997]
MLKRIGIKYQLRITTLIPAFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRRDDRTLQGLINASTINP
EVIALAFYSSDGQLLAYRGGKHSLNKPFNPPKFTGDYIESKQINPFTINFIAPVTIPKFNLYSSSPLKKLLSPMATRADD
ILGWLSIDIDTRSMIIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYLPISRLRRSMKQILRNEFETEIKTTSPGELGI
IEQGCAHLQKKYLETIRDLNQHIEVATEDLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKASAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLTLAAPTAHKKGIDLIPITD
VNVPKIILGDPFRIKQFITNLVTNAVKFTDHGYVLVRTKVEQETDKDYTLSITITDTGLGISPEDQSKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISFTSELNKGSSFTAQVKVEKLAAYEIEKNQIHPFAQFKMLCFDDNSLHLEALCNG
LGYWGIQCVAVNSFNRLAKALENNKDCKIAFLNINKGYEQKIGKLISENNYFPYVLVSKWLINDYTALGAQGFLYKPISI
QKLQDVIESLTSLENVEKPTNHELDSLREQLRFMRLNLLIAEDNPVNKMLLNSLLGTHADMTAVDDGEMAVSACNDKKFD
LILLDLQMPKINGLEASRLIRQKSQLNRHTPIVLISANGRDVNSIDLKKSGVDFCLQKPIDEKQLLTQIIRIADKAKHAA
IDWQLCVQKVSGNQALAEEFLARFVEELHQNREEFIQLMHDKNIKKLGEAAHKLHGACCFSGVPTLQKKVVHVEKLAAHA
ASIEELATPFAELIQSIDAVINEYENQKIRI

Nucleotide

• Length: 2736 bp

>NTDB_id=470914 HBNCFIEN_RS10030 WP_182393670.1 2335033..2337768(+) (letS) [Legionella sp. PC997]
ATCTTGAAACGCATTGGTATTAAGTATCAACTGAGAATTACCACCCTCATTCCAGCCTTTCTAGTCGCCCTGCTCCTCGC
TATTTTTTATAATGGACTATTTGGTAATGACTTAAAGCAACACATGTCCCGATTAGGAGAAGCGTATATCCGCCAACTAT
TACCTGCAGCACAATATGCTATGCTGCGGCGTGATGATCGTACTTTACAGGGTTTAATTAATGCATCCACCATTAATCCC
GAAGTAATCGCACTTGCCTTTTACAGTAGTGATGGACAATTACTTGCATATCGCGGTGGAAAACACTCTTTGAATAAACC
GTTTAATCCCCCTAAATTCACGGGAGATTACATTGAAAGCAAACAAATAAATCCTTTTACGATTAATTTTATTGCACCCG
TTACTATTCCAAAATTCAATCTTTATTCCAGCTCCCCTCTCAAGAAGCTCTTAAGCCCCATGGCCACACGGGCGGATGAC
ATTCTAGGATGGTTATCCATCGATATTGATACGCGTTCTATGATAATAAAACGCTATCAAATGCTCATCGTTACCATCTT
TATTACCTTATTTGGTTTGCTAATGGGACTAACCATTCACTATTTTCTTTCCAAACGTATTTATTTACCTATTTCCCGTT
TACGTCGAAGTATGAAGCAAATTTTACGGAATGAATTTGAAACCGAAATTAAAACAACAAGTCCAGGTGAGTTAGGCATT
ATTGAGCAAGGTTGTGCTCATCTGCAAAAAAAATACCTCGAAACAATCCGGGATTTGAATCAACATATTGAAGTTGCTAC
TGAAGATTTACAACAAAGTCTCGAACTGCTGGAAGAAAAAAATATTGAACTCTCACTTGAAAAGAAGAAAATTGAAGAAA
AAAGCCGGCAAAAATCAGAATTTATTGCCAATATGAGCCATGAAATCCGTACACCGATGAATGGAGTAATTGGATTCACC
AATGTTTTATTGGAAAGCAAGCTTGATCCATTACAATTGGATTATGTAAAAACGATCAAAGCCTCTGCCCAAGATTTATT
AGGAATAATTAACGACATTCTTGATTTTTCCAAAATCGATGCCGGAAAGCTTCATCTAGATTGCATTCCGTTAAATATTC
GTCACTGTATTGATGAAGTTCTTACTCTTGCAGCGCCCACTGCTCATAAAAAGGGAATTGATTTAATTCCTATAACCGAT
GTCAATGTACCCAAAATTATTTTAGGCGATCCTTTTAGGATCAAGCAATTTATTACTAATTTGGTGACCAATGCGGTTAA
ATTTACCGATCATGGTTATGTGTTAGTTCGCACAAAAGTAGAGCAAGAAACTGATAAGGATTACACTTTAAGTATCACAA
TTACCGATACAGGTCTGGGTATTTCTCCTGAGGATCAAAGTAAACTATTTACAGCCTTTAACCAGGCAGATACAAGCATT
ACGCGTCGATATGGCGGCTCGGGTCTTGGTTTGGTTATTTGCAAAAAACTTTGTGAAGAAATGCATGGCCGTATTTCTTT
TACCAGTGAACTCAATAAAGGCTCAAGCTTTACTGCTCAGGTCAAAGTTGAAAAGCTGGCTGCTTATGAAATAGAAAAAA
ATCAAATACACCCTTTCGCTCAGTTTAAAATGTTGTGCTTTGATGATAATTCCCTGCATTTAGAAGCGCTTTGTAATGGT
TTAGGTTATTGGGGAATACAATGTGTCGCGGTCAACTCCTTTAATCGTCTTGCGAAGGCTCTGGAGAATAACAAAGACTG
TAAAATTGCATTTCTCAATATTAACAAAGGCTATGAACAAAAAATTGGCAAACTAATCTCAGAAAATAATTATTTCCCCT
ATGTATTGGTTTCTAAATGGCTTATTAATGATTATACCGCGCTTGGAGCTCAAGGATTTTTATATAAGCCAATTAGTATT
CAAAAACTTCAAGATGTAATTGAATCGCTTACCAGCTTAGAAAATGTTGAAAAACCAACAAATCATGAATTAGATAGCCT
AAGGGAGCAACTACGTTTTATGCGGCTTAATTTGCTCATTGCAGAAGATAACCCAGTGAACAAAATGCTTCTTAACTCGC
TATTAGGTACTCATGCAGACATGACTGCGGTAGACGACGGTGAGATGGCTGTCTCGGCTTGTAATGACAAAAAGTTTGAT
CTCATTTTACTTGACTTACAAATGCCTAAAATAAATGGATTAGAAGCGTCTCGGCTCATTCGTCAAAAATCACAACTTAA
TCGGCATACCCCCATTGTTTTAATCAGTGCAAATGGAAGAGATGTGAATAGTATTGACTTGAAAAAATCGGGCGTCGATT
TTTGTTTGCAAAAACCTATTGATGAAAAACAATTACTCACCCAAATCATTCGAATCGCCGATAAAGCAAAACATGCTGCG
ATTGATTGGCAATTATGCGTACAGAAAGTTTCAGGAAATCAAGCGTTGGCAGAAGAGTTTCTTGCGCGCTTTGTGGAAGA
ATTACATCAGAACCGAGAAGAATTCATTCAATTAATGCATGATAAAAACATTAAAAAATTAGGAGAAGCGGCTCATAAAC
TTCATGGAGCATGTTGTTTTTCCGGCGTGCCCACATTACAGAAAAAAGTAGTTCATGTAGAAAAACTGGCTGCACATGCT
GCTTCAATTGAAGAGTTGGCTACTCCTTTTGCCGAATTAATTCAGAGTATTGATGCAGTGATAAATGAATATGAAAATCA
AAAAATAAGAATTTAA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (819-901)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Response regulator receiver domain (Response_reg) (679-789)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	78.831	99.561	0.785