Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   H3L94_RS10080 Genome accession   NZ_CP059567
Coordinates   2059266..2060825 (-) Length   519 a.a.
NCBI ID   WP_182121910.1    Uniprot ID   A0A7D7N4X1
Organism   Neisseria shayeganii strain DSM 22244     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2054266..2065825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L94_RS10050 (H3L94_10050) - 2054697..2055164 (-) 468 WP_156787046.1 winged helix-turn-helix transcriptional regulator -
  H3L94_RS10055 (H3L94_10055) - 2055299..2056555 (+) 1257 WP_182121906.1 D-amino acid dehydrogenase -
  H3L94_RS10060 (H3L94_10060) - 2056707..2056997 (-) 291 WP_009119767.1 hypothetical protein -
  H3L94_RS10065 (H3L94_10065) - 2057108..2057998 (-) 891 WP_182121907.1 NUDIX domain-containing protein -
  H3L94_RS10070 (H3L94_10070) - 2058004..2058447 (-) 444 WP_182121908.1 hypothetical protein -
  H3L94_RS10075 (H3L94_10075) - 2058450..2059202 (-) 753 WP_182121909.1 class I SAM-dependent methyltransferase -
  H3L94_RS10080 (H3L94_10080) pilR 2059266..2060825 (-) 1560 WP_182121910.1 sigma-54 dependent transcriptional regulator Regulator
  H3L94_RS10085 (H3L94_10085) - 2060818..2062416 (-) 1599 WP_182121911.1 HAMP domain-containing sensor histidine kinase -
  H3L94_RS10090 (H3L94_10090) parC 2062413..2064716 (-) 2304 WP_182121912.1 DNA topoisomerase IV subunit A -
  H3L94_RS12665 - 2064864..2065037 (+) 174 Protein_2076 lipoprotein signal peptidase -

Sequence

Protein


Download         Length: 519 a.a.        Molecular weight: 57141.30 Da        Isoelectric Point: 5.4266

>NTDB_id=470785 H3L94_RS10080 WP_182121910.1 2059266..2060825(-) (pilR) [Neisseria shayeganii strain DSM 22244]
MNKNSLQKPVLVVDDEQDIRDLMEMTLMKMGLSVETAHGVAAAKQWLAEKKFSLVLTDMRMPDGSGLEVVEYINEQALDV
PVAVITAFGNADQAVQAIKAGAFDYLQKPITLAQLRTLVKSAVKINEEDRRPPASDPEPEPSAAEEILPPPAPAPKRASP
QPKAAASVPPPAPPAGQKDIPRLIGHSPQIEEARQMIRKLAHTTVPVYISGESGSGKEQAARSIHELSDRREQPFVAVNC
GAIPENLMESEFFGYKKGSFTGADQDRLGFFQHAHGGTLFLDEVADLPLHMQVKLLRAIQEKAVRRIGDAQEVKVDVRII
SATHKDLAALVAKGAFRQDLFYRLNVVSLTMPPLREMREDLPKLIMQLLRKHRQGGDYQLTQAAKQALLQYSYPGNFREL
ENILERAVALAVNQTIDAQDLQLTSSPLLQEEDDWGSALAAANGGAEEAVPAAEAGEAVGGLADFVLGRTQIQDYLDDVE
RAIIEQALQKTRYNRTQAAKLLGISFRSMRYRMERLNIE

Nucleotide


Download         Length: 1560 bp        

>NTDB_id=470785 H3L94_RS10080 WP_182121910.1 2059266..2060825(-) (pilR) [Neisseria shayeganii strain DSM 22244]
ATGAATAAAAACAGCTTGCAAAAACCCGTTTTGGTGGTGGACGACGAGCAGGACATCCGCGATCTGATGGAAATGACGCT
GATGAAAATGGGCTTGTCGGTAGAAACCGCCCACGGCGTGGCGGCCGCCAAACAATGGCTGGCCGAAAAGAAATTCTCCT
TGGTGCTGACCGATATGCGGATGCCCGACGGCTCCGGTTTGGAAGTGGTGGAATACATCAACGAGCAGGCTTTGGATGTG
CCGGTGGCGGTGATCACCGCTTTCGGCAATGCCGATCAGGCGGTGCAGGCCATCAAAGCCGGCGCCTTCGACTATCTGCA
AAAACCGATCACGCTGGCCCAGCTGCGCACTTTGGTCAAGTCGGCGGTGAAAATCAACGAAGAAGACCGCCGCCCGCCCG
CATCCGATCCCGAGCCGGAGCCATCTGCGGCAGAGGAGATTTTGCCGCCGCCGGCGCCGGCTCCCAAACGCGCGTCGCCG
CAGCCTAAGGCCGCAGCGTCCGTTCCGCCGCCCGCGCCGCCGGCAGGGCAAAAGGACATTCCGCGCCTCATCGGCCATTC
GCCGCAGATTGAAGAAGCCCGGCAGATGATCCGCAAGCTCGCCCACACCACGGTGCCGGTTTATATTTCCGGCGAATCCG
GTTCCGGTAAAGAGCAGGCCGCGCGCAGCATTCACGAGCTGTCCGACCGCCGCGAGCAGCCTTTTGTGGCGGTCAACTGC
GGGGCAATTCCGGAAAACCTGATGGAAAGCGAGTTTTTCGGCTACAAAAAAGGCAGCTTTACCGGCGCCGACCAAGACCG
CTTGGGCTTTTTCCAGCACGCCCACGGCGGCACGCTGTTTCTCGACGAAGTGGCCGATCTGCCGCTGCACATGCAGGTGA
AGCTGCTGCGGGCGATTCAGGAAAAAGCCGTGCGCCGCATCGGCGATGCGCAGGAAGTGAAGGTGGACGTGCGCATCATT
TCCGCCACCCATAAAGATTTGGCCGCCTTGGTGGCCAAAGGTGCTTTCCGCCAAGACTTGTTTTACCGTCTCAACGTGGT
GTCGCTCACCATGCCGCCTTTGCGCGAAATGCGCGAAGACCTGCCCAAGCTGATCATGCAGCTCTTGCGCAAACACCGCC
AGGGCGGCGACTACCAGCTGACTCAGGCCGCCAAGCAGGCCCTACTGCAATACAGCTATCCCGGCAACTTCCGCGAGCTG
GAAAACATTCTCGAGCGCGCGGTGGCTTTGGCGGTCAACCAAACCATCGACGCACAAGACCTGCAGCTCACCAGTTCGCC
GCTATTGCAGGAAGAGGACGACTGGGGCAGCGCCTTGGCCGCCGCCAACGGCGGGGCCGAGGAAGCCGTGCCGGCGGCCG
AGGCGGGCGAAGCGGTGGGCGGCTTGGCCGACTTCGTGCTGGGGCGCACCCAGATTCAAGACTATCTTGACGATGTCGAA
CGCGCCATCATTGAGCAGGCGCTGCAGAAAACCCGTTACAACCGCACTCAGGCCGCGAAACTGCTCGGCATCAGCTTCCG
CTCCATGCGCTACCGCATGGAACGCCTGAACATCGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(10-119)

Sigma-54 interaction domain (Sigma54_activat)

(183-349)

Bacterial regulatory protein, Fis family (HTH_8)

(476-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7D7N4X1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

48.842

99.807

0.487
  pilR Acinetobacter baumannii strain A118

42.166

99.615

0.42