Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K12_RS01820 Genome accession   NZ_CP069865
Coordinates   211120..211776 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1282     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 206120..216776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K12_RS01780 (I6K12_01785) - 206626..206886 (+) 261 WP_000488113.1 ogr/Delta-like zinc finger family protein -
  I6K12_RS01785 (I6K12_01790) - 207077..207217 (+) 141 WP_000078920.1 Hok/Gef family protein -
  I6K12_RS01790 (I6K12_01795) - 207409..207690 (-) 282 WP_071589622.1 hypothetical protein -
  I6K12_RS01810 (I6K12_01815) pgsA 208686..209234 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K12_RS01815 (I6K12_01820) uvrC 209291..211123 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6K12_RS01820 (I6K12_01825) letA 211120..211776 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K12_RS01825 (I6K12_01830) yecU 212072..212248 (+) 177 WP_000590347.1 protein YecU -
  I6K12_RS01830 (I6K12_01835) yecF 212235..212459 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K12_RS01835 (I6K12_01840) sdiA 212526..213248 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  I6K12_RS01840 (I6K12_01845) tcyN 213478..214230 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K12_RS01845 (I6K12_01850) tcyL 214227..214895 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K12_RS01850 (I6K12_01855) dcyD 214910..215896 (-) 987 WP_020232905.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=470698 I6K12_RS01820 WP_000611328.1 211120..211776(-) (letA) [Escherichia coli strain FDAARGOS_1282]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=470698 I6K12_RS01820 WP_000611328.1 211120..211776(-) (letA) [Escherichia coli strain FDAARGOS_1282]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482