Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D1098_RS06180 Genome accession   NZ_CP069797
Coordinates   1344999..1346831 (-) Length   610 a.a.
NCBI ID   WP_009874684.1    Uniprot ID   A3MYZ9
Organism   Actinobacillus pleuropneumoniae strain K17     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1339999..1351831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1098_RS06165 (D1098_06190) potA 1340574..1341689 (-) 1116 WP_005600350.1 spermidine/putrescine ABC transporter ATP-binding protein PotA -
  D1098_RS06170 (D1098_06195) rep 1342023..1344041 (+) 2019 WP_009874682.1 DNA helicase Rep -
  D1098_RS06175 (D1098_06200) - 1344178..1344930 (-) 753 WP_009874683.1 TatD family hydrolase -
  D1098_RS06180 (D1098_06205) uvrC 1344999..1346831 (-) 1833 WP_009874684.1 excinuclease ABC subunit UvrC Machinery gene
  D1098_RS06185 (D1098_06210) - 1346984..1348954 (-) 1971 WP_005596175.1 TonB-dependent receptor domain-containing protein -
  D1098_RS06190 (D1098_06215) pgsA 1349074..1349625 (-) 552 WP_011848342.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D1098_RS06195 (D1098_06220) - 1349807..1350472 (+) 666 WP_011848341.1 Bax inhibitor-1 family protein -
  D1098_RS06200 (D1098_06225) - 1350525..1350860 (+) 336 WP_009875442.1 TusE/DsrC/DsvC family sulfur relay protein -
  D1098_RS06205 (D1098_06230) - 1350927..1351823 (+) 897 WP_009875443.1 metal ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 69100.98 Da        Isoelectric Point: 9.0241

>NTDB_id=470441 D1098_RS06180 WP_009874684.1 1344999..1346831(-) (uvrC) [Actinobacillus pleuropneumoniae strain K17]
MFDAKAFLADVPHLPGVYRMYDAKNTIIYVGKAKDLKKRLSSYFRSQLASKKTEALVANIHHIETTITHSETEALLLEHN
YIKENQPKYNVLLRDDKSYPYILLTKHQHPRITSFRGSKKVAGEYFGPYPNAGAVRETLNLLQKLFPIRQCEDSYYKNRS
RPCLQYQIGRCLAPCVEGYYSQAEYDNQVNLVRLFLQGKDGQVVEHLVQKMENAAQELDFEAAARFRDQIQSVRAVQEKQ
FVSNERLDDLDIISIAYQHGIACVHILFVRHGKVLGNRSYFPKVPNNTDLSELADTFVGQFYLQMNQHRTIPNQIIIDQS
LSEVTALANVLSEQAGHKVSIADKNIRGDKSRYLALAKTNAEAALTLQLKQDTHIRQRYDSLKALLNLAEIKRMECFDIS
HTMGNQTVASCVVFDKNGPLKSDYRRFNIEGITGGDDYAAMEQALLKLYDRNLEEEKIPDIIFIDGGKGQLNRALETFTS
LNVSWDKRKPLLVGVAKGVERKAGLETLLISKWDKEIHLPPDSPALHLIQHIRDESHNHAITGHRKKRQKAFTESGLESI
AGVGAKRRQALLKYLGGMQGVKAATLEEIQSVPGISKQLAEVIFDTLQHS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=470441 D1098_RS06180 WP_009874684.1 1344999..1346831(-) (uvrC) [Actinobacillus pleuropneumoniae strain K17]
ATGTTTGATGCCAAAGCCTTTCTTGCCGATGTTCCTCATCTCCCCGGTGTTTACCGTATGTATGATGCGAAAAATACTAT
TATCTATGTCGGTAAAGCCAAAGATCTTAAAAAACGCTTATCCAGTTATTTTCGTAGCCAACTTGCCAGTAAGAAAACCG
AGGCGTTAGTCGCTAACATTCATCATATCGAAACCACGATTACCCATTCGGAAACGGAAGCGTTACTACTTGAACATAAT
TACATTAAAGAGAATCAGCCGAAGTACAACGTGCTTTTGCGTGACGATAAATCCTATCCGTATATTTTACTCACAAAGCA
TCAACATCCCCGAATTACTTCGTTTCGTGGTAGTAAAAAAGTTGCCGGTGAATATTTTGGCCCGTATCCGAATGCAGGTG
CAGTGCGTGAAACGCTAAACTTGCTGCAAAAACTGTTTCCGATTCGCCAATGTGAAGACAGCTACTATAAAAATCGTTCT
CGCCCTTGTTTGCAATACCAAATTGGGCGTTGTCTTGCCCCTTGTGTAGAAGGTTATTACTCACAAGCGGAATATGATAA
CCAAGTAAATTTAGTCCGTTTGTTTTTACAAGGTAAAGACGGACAAGTGGTTGAGCATTTGGTACAAAAAATGGAAAACG
CTGCGCAAGAGCTGGATTTTGAAGCGGCGGCTCGTTTTCGCGATCAGATCCAATCGGTACGAGCGGTGCAAGAAAAACAA
TTTGTCTCTAACGAACGTTTGGATGATTTGGATATTATTTCGATCGCTTATCAACACGGTATTGCTTGCGTACATATTTT
ATTTGTGCGTCACGGTAAGGTATTGGGTAATCGTTCCTATTTTCCTAAAGTGCCGAACAATACCGATTTAAGCGAGTTGG
CGGATACCTTTGTCGGTCAGTTTTATTTACAAATGAACCAACATCGCACGATACCGAATCAAATTATTATCGATCAGTCG
TTAAGTGAAGTGACTGCATTAGCTAATGTGCTGTCCGAACAAGCGGGGCATAAAGTCAGTATTGCCGATAAAAATATTCG
TGGCGATAAAAGCCGCTATTTGGCATTAGCAAAAACCAATGCGGAAGCCGCGCTTACTTTGCAACTTAAACAAGATACGC
ATATTCGTCAGCGTTATGATTCGCTCAAGGCATTACTCAATTTAGCGGAAATCAAGCGAATGGAGTGTTTCGATATTTCT
CACACAATGGGTAATCAAACGGTAGCTTCTTGTGTCGTATTTGATAAAAATGGGCCGCTAAAATCGGATTACCGCCGTTT
TAATATTGAAGGTATTACCGGTGGTGATGACTATGCGGCAATGGAACAAGCCTTATTAAAACTTTATGACCGCAATTTAG
AAGAAGAAAAAATTCCGGATATTATTTTTATTGATGGTGGGAAAGGTCAGCTGAATCGAGCGTTGGAAACCTTTACTTCG
TTAAATGTCAGTTGGGATAAGCGCAAACCGTTGTTAGTTGGTGTGGCGAAAGGAGTAGAGCGAAAAGCCGGTTTAGAAAC
TTTATTGATCAGCAAATGGGATAAGGAAATTCACTTACCGCCGGACAGTCCCGCACTACATTTGATTCAACATATTCGTG
ACGAATCGCATAATCACGCAATAACCGGACACCGTAAAAAGCGCCAAAAAGCCTTTACGGAAAGTGGCTTAGAATCAATC
GCCGGTGTTGGAGCAAAACGTCGCCAAGCGTTACTGAAATACCTCGGCGGAATGCAGGGCGTGAAAGCCGCAACTTTAGA
AGAAATTCAATCCGTACCCGGTATTTCAAAGCAACTTGCCGAAGTGATTTTTGATACGTTACAGCATAGCTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(202-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3MYZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.11

99.836

0.37
  uvrC Streptococcus pneumoniae R6

36.782

99.836

0.367
  uvrC Streptococcus pneumoniae D39

36.782

99.836

0.367