Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JSQ74_RS05170 Genome accession   NZ_CP069710
Coordinates   1060330..1060986 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EA2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1055330..1065986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JSQ74_RS05140 (JSQ74_05140) yecA 1056581..1057246 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  JSQ74_RS05160 (JSQ74_05160) pgsA 1057899..1058444 (-) 546 WP_048948292.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JSQ74_RS05165 (JSQ74_05165) uvrC 1058501..1060333 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JSQ74_RS05170 (JSQ74_05170) letA 1060330..1060986 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JSQ74_RS05175 (JSQ74_05175) yecU 1061282..1061458 (+) 177 WP_000590344.1 protein YecU -
  JSQ74_RS05180 (JSQ74_05180) yecF 1061445..1061669 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JSQ74_RS05185 (JSQ74_05185) sdiA 1061737..1062459 (-) 723 WP_001154283.1 transcriptional regulator SdiA -
  JSQ74_RS05190 (JSQ74_05190) tcyN 1062689..1063441 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JSQ74_RS05195 (JSQ74_05195) tcyL 1063438..1064106 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JSQ74_RS05200 (JSQ74_05200) dcyD 1064121..1065107 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=469993 JSQ74_RS05170 WP_000611328.1 1060330..1060986(-) (letA) [Escherichia coli strain EA2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=469993 JSQ74_RS05170 WP_000611328.1 1060330..1060986(-) (letA) [Escherichia coli strain EA2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482