Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JSQ86_RS09805 Genome accession   NZ_CP069707
Coordinates   2022396..2023052 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E41     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017396..2028052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JSQ86_RS09775 (JSQ86_09775) dcyD 2018275..2019261 (+) 987 WP_001128227.1 D-cysteine desulfhydrase -
  JSQ86_RS09780 (JSQ86_09780) tcyL 2019276..2019944 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JSQ86_RS09785 (JSQ86_09785) tcyN 2019941..2020693 (+) 753 WP_113078360.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JSQ86_RS09790 (JSQ86_09790) sdiA 2020923..2021645 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  JSQ86_RS09795 (JSQ86_09795) yecF 2021713..2021937 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JSQ86_RS09800 (JSQ86_09800) yecU 2021924..2022100 (-) 177 WP_000590347.1 protein YecU -
  JSQ86_RS24430 - 2022138..2022254 (-) 117 WP_001302039.1 hypothetical protein -
  JSQ86_RS09805 (JSQ86_09805) letA 2022396..2023052 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JSQ86_RS09810 (JSQ86_09810) uvrC 2023049..2024881 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JSQ86_RS09815 (JSQ86_09815) pgsA 2024938..2025486 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JSQ86_RS09835 (JSQ86_09835) yecA 2026136..2026801 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=469854 JSQ86_RS09805 WP_000611328.1 2022396..2023052(+) (letA) [Escherichia coli strain E41]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=469854 JSQ86_RS09805 WP_000611328.1 2022396..2023052(+) (letA) [Escherichia coli strain E41]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482