Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYE   Type   Machinery gene
Locus tag   H1R75_RS00965 Genome accession   NZ_CP059471
Coordinates   142052..142345 (+) Length   97 a.a.
NCBI ID   WP_182001488.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 103364..151640 142052..142345 within 0


Gene organization within MGE regions


Location: 103364..151640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS00680 (H1R75_00680) - 103364..104800 (-) 1437 WP_182001825.1 recombinase family protein -
  H1R75_RS00685 (H1R75_00685) - 104939..105679 (-) 741 WP_182001455.1 hypothetical protein -
  H1R75_RS00690 (H1R75_00690) - 105730..106464 (-) 735 WP_182001456.1 XRE family transcriptional regulator -
  H1R75_RS00695 (H1R75_00695) - 106657..106863 (+) 207 WP_039697363.1 helix-turn-helix transcriptional regulator -
  H1R75_RS00700 (H1R75_00700) - 107118..107261 (+) 144 WP_180367884.1 BOW99_gp33 family protein -
  H1R75_RS00705 (H1R75_00705) - 107361..107612 (+) 252 WP_118101029.1 transcriptional regulator -
  H1R75_RS00710 (H1R75_00710) - 107736..108116 (+) 381 WP_182001457.1 DnaD domain-containing protein -
  H1R75_RS00715 (H1R75_00715) - 108126..108383 (+) 258 WP_182001458.1 hypothetical protein -
  H1R75_RS00720 (H1R75_00720) - 108386..108610 (+) 225 WP_043895081.1 hypothetical protein -
  H1R75_RS00725 (H1R75_00725) - 108607..108756 (+) 150 WP_182001459.1 hypothetical protein -
  H1R75_RS00730 (H1R75_00730) - 108744..109418 (+) 675 WP_182001460.1 ERF family protein -
  H1R75_RS00735 (H1R75_00735) - 109430..110443 (+) 1014 WP_182001461.1 DUF1351 domain-containing protein -
  H1R75_RS00740 (H1R75_00740) - 110440..110607 (+) 168 WP_182001462.1 hypothetical protein -
  H1R75_RS00745 (H1R75_00745) - 110746..110952 (+) 207 WP_182001463.1 hypothetical protein -
  H1R75_RS00750 (H1R75_00750) - 110962..111192 (+) 231 WP_182001464.1 hypothetical protein -
  H1R75_RS00755 (H1R75_00755) - 111198..111977 (+) 780 WP_039697398.1 DNA methyltransferase -
  H1R75_RS00760 (H1R75_00760) - 111974..112189 (+) 216 WP_039697372.1 hypothetical protein -
  H1R75_RS00765 (H1R75_00765) - 112186..112923 (+) 738 WP_182001465.1 ORF6C domain-containing protein -
  H1R75_RS00770 (H1R75_00770) - 112933..113151 (+) 219 WP_148525567.1 hypothetical protein -
  H1R75_RS00775 (H1R75_00775) - 113138..113386 (+) 249 WP_148525565.1 hypothetical protein -
  H1R75_RS09890 - 113647..113778 (+) 132 WP_268926161.1 hypothetical protein -
  H1R75_RS00780 (H1R75_00780) - 113780..113992 (+) 213 WP_182001466.1 crAss001_48 related protein -
  H1R75_RS00785 (H1R75_00785) - 114029..114583 (+) 555 WP_328804807.1 hypothetical protein -
  H1R75_RS00790 (H1R75_00790) - 114576..114791 (+) 216 WP_182001467.1 hypothetical protein -
  H1R75_RS00795 (H1R75_00795) - 114793..115029 (+) 237 WP_020917136.1 hypothetical protein -
  H1R75_RS00800 (H1R75_00800) - 115038..115430 (+) 393 WP_148525557.1 hypothetical protein -
  H1R75_RS00805 (H1R75_00805) - 115505..115987 (+) 483 WP_143888178.1 terminase small subunit -
  H1R75_RS00810 (H1R75_00810) - 115977..117287 (+) 1311 WP_020917133.1 PBSX family phage terminase large subunit -
  H1R75_RS00815 (H1R75_00815) - 117297..118847 (+) 1551 WP_182001468.1 phage portal protein -
  H1R75_RS00820 (H1R75_00820) - 118840..119979 (+) 1140 Protein_109 phage minor capsid protein -
  H1R75_RS00825 (H1R75_00825) - 120339..120569 (+) 231 WP_182001470.1 hypothetical protein -
  H1R75_RS00830 (H1R75_00830) - 120730..121287 (+) 558 WP_143888182.1 phage scaffolding protein -
  H1R75_RS00835 (H1R75_00835) - 121301..122173 (+) 873 WP_182001471.1 hypothetical protein -
  H1R75_RS00840 (H1R75_00840) - 122184..122363 (+) 180 WP_020917127.1 hypothetical protein -
  H1R75_RS00845 (H1R75_00845) - 122363..122623 (+) 261 WP_148525546.1 hypothetical protein -
  H1R75_RS00850 (H1R75_00850) - 122654..123046 (+) 393 WP_182001472.1 hypothetical protein -
  H1R75_RS00855 (H1R75_00855) - 123036..123362 (+) 327 WP_043895078.1 putative minor capsid protein -
  H1R75_RS00860 (H1R75_00860) - 123362..123709 (+) 348 WP_182001473.1 minor capsid protein -
  H1R75_RS00865 (H1R75_00865) - 123709..124107 (+) 399 WP_182001474.1 minor capsid protein -
  H1R75_RS00870 (H1R75_00870) - 124118..124576 (+) 459 WP_182001475.1 phage tail tube protein -
  H1R75_RS00875 (H1R75_00875) - 124590..124967 (+) 378 WP_182001476.1 hypothetical protein -
  H1R75_RS00880 (H1R75_00880) - 124967..125548 (+) 582 WP_182001477.1 bacteriophage Gp15 family protein -
  H1R75_RS00885 (H1R75_00885) - 125563..129513 (+) 3951 WP_182001478.1 tape measure protein -
  H1R75_RS00890 (H1R75_00890) - 129510..130997 (+) 1488 WP_182001479.1 distal tail protein Dit -
  H1R75_RS00895 (H1R75_00895) - 130998..132176 (+) 1179 Protein_124 phage tail spike protein -
  H1R75_RS00900 (H1R75_00900) - 132774..133892 (+) 1119 WP_118101006.1 hypothetical protein -
  H1R75_RS00905 (H1R75_00905) - 133908..134153 (+) 246 WP_182001481.1 hypothetical protein -
  H1R75_RS00910 (H1R75_00910) - 134098..136212 (+) 2115 WP_182001482.1 hypothetical protein -
  H1R75_RS00915 (H1R75_00915) - 136227..138305 (+) 2079 WP_182001483.1 DUF859 family phage minor structural protein -
  H1R75_RS00920 (H1R75_00920) - 138318..138659 (+) 342 WP_118101002.1 DUF1366 domain-containing protein -
  H1R75_RS00925 (H1R75_00925) - 138685..138843 (+) 159 WP_182001484.1 hypothetical protein -
  H1R75_RS00930 (H1R75_00930) - 138865..139197 (+) 333 WP_020917109.1 hypothetical protein -
  H1R75_RS00935 (H1R75_00935) - 139210..139536 (+) 327 WP_111698489.1 phage holin -
  H1R75_RS00940 (H1R75_00940) - 139533..140378 (+) 846 WP_182001485.1 lytic exoenzyme target recognition domain-containing protein -
  H1R75_RS00945 (H1R75_00945) - 140889..141035 (+) 147 WP_180367887.1 hypothetical protein -
  H1R75_RS00950 (H1R75_00950) - 141185..141385 (+) 201 WP_148525789.1 XRE family transcriptional regulator -
  H1R75_RS00955 (H1R75_00955) comYC 141450..141683 (+) 234 WP_182001486.1 competence type IV pilus major pilin ComGC Machinery gene
  H1R75_RS00960 (H1R75_00960) comGD 141667..142098 (+) 432 WP_182001487.1 competence type IV pilus minor pilin ComGD -
  H1R75_RS00965 (H1R75_00965) comYE 142052..142345 (+) 294 WP_182001488.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1R75_RS00970 (H1R75_00970) comYF 142329..142766 (+) 438 WP_003067903.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1R75_RS00975 (H1R75_00975) comGG 142795..143088 (+) 294 WP_234704406.1 competence type IV pilus minor pilin ComGG -
  H1R75_RS00980 (H1R75_00980) comYH 143142..144098 (+) 957 WP_182001489.1 class I SAM-dependent methyltransferase Machinery gene
  H1R75_RS00985 (H1R75_00985) - 144152..145351 (+) 1200 WP_182001490.1 acetate kinase -
  H1R75_RS00990 (H1R75_00990) - 145509..145706 (+) 198 WP_027968026.1 helix-turn-helix transcriptional regulator -
  H1R75_RS00995 (H1R75_00995) - 145762..146214 (+) 453 WP_074483978.1 ABC transporter permease -
  H1R75_RS01000 (H1R75_01000) - 146226..146861 (+) 636 WP_182001491.1 CPBP family intramembrane glutamic endopeptidase -
  H1R75_RS01005 (H1R75_01005) proC 146913..147683 (-) 771 WP_182001492.1 pyrroline-5-carboxylate reductase -
  H1R75_RS01010 (H1R75_01010) pepA 147745..148812 (-) 1068 WP_074483975.1 glutamyl aminopeptidase -
  H1R75_RS01015 (H1R75_01015) - 148929..149222 (+) 294 WP_182001493.1 DUF4651 domain-containing protein -
  H1R75_RS01020 (H1R75_01020) - 149215..149532 (+) 318 WP_021141448.1 thioredoxin family protein -
  H1R75_RS01025 (H1R75_01025) ytpR 149541..150167 (+) 627 WP_182001494.1 YtpR family tRNA-binding protein -
  H1R75_RS01030 (H1R75_01030) ssbA 150265..150660 (+) 396 WP_021141449.1 single-stranded DNA-binding protein Machinery gene
  H1R75_RS01035 (H1R75_01035) - 150840..151640 (+) 801 WP_039697668.1 Cof-type HAD-IIB family hydrolase -

Sequence


Protein


Download         Length: 97 a.a.        Molecular weight: 10959.82 Da        Isoelectric Point: 6.8788

>NTDB_id=469802 H1R75_RS00965 WP_182001488.1 142052..142345(+) (comYE) [Streptococcus equinus strain MDC1]
MVIIKRQKLKAYILLESLAALALLATITILVLGEMDKSRHQMQDSLHQQEVLNVATMAAQTGQDDLVMNGVEVHITRRDG
ELYVYDGQKEVMHVKKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=469802 H1R75_RS00965 WP_182001488.1 142052..142345(+) (comYE) [Streptococcus equinus strain MDC1]
GTGGTAATTATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGTTTGGCTGCTTTAGCTTTGCTAGCTACCAT
TACAATTCTTGTTTTGGGAGAAATGGATAAAAGTCGCCACCAGATGCAAGACAGCTTACATCAGCAAGAGGTTCTCAATG
TTGCTACTATGGCTGCTCAGACAGGGCAAGATGACTTGGTGATGAATGGTGTTGAGGTTCATATTACTAGACGAGACGGA
GAACTTTATGTCTACGATGGGCAAAAAGAGGTGATGCATGTTAAGAAGAACTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

48.958

98.969

0.485

  comYE Streptococcus mutans UA159

48.958

98.969

0.485

  comGE/cglE Streptococcus pneumoniae Rx1

40.86

95.876

0.392

  comGE/cglE Streptococcus pneumoniae D39

40.86

95.876

0.392

  comGE/cglE Streptococcus pneumoniae R6

40.86

95.876

0.392

  comGE/cglE Streptococcus pneumoniae TIGR4

40.86

95.876

0.392

  comGE/cglE Streptococcus mitis SK321

39.785

95.876

0.381

  comGE/cglE Streptococcus mitis NCTC 12261

39.785

95.876

0.381