Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JSU10_RS09900 Genome accession   NZ_CP069692
Coordinates   2069394..2070050 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli H20 strain MIN6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064394..2075050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JSU10_RS09870 (JSU10_09870) dcyD 2065273..2066259 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JSU10_RS09875 (JSU10_09875) tcyL 2066274..2066942 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JSU10_RS09880 (JSU10_09880) tcyN 2066939..2067691 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JSU10_RS09885 (JSU10_09885) sdiA 2067921..2068643 (+) 723 WP_103262141.1 transcriptional regulator SdiA -
  JSU10_RS09890 (JSU10_09890) yecF 2068711..2068935 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JSU10_RS09895 (JSU10_09895) yecU 2068922..2069098 (-) 177 WP_000590344.1 protein YecU -
  JSU10_RS25695 - 2069136..2069252 (-) 117 WP_001302039.1 hypothetical protein -
  JSU10_RS09900 (JSU10_09900) letA 2069394..2070050 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JSU10_RS09905 (JSU10_09905) uvrC 2070047..2071879 (+) 1833 WP_103262142.1 excinuclease ABC subunit UvrC Machinery gene
  JSU10_RS09910 (JSU10_09910) pgsA 2071936..2072484 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JSU10_RS09930 (JSU10_09930) - 2073179..2073919 (-) 741 WP_072663995.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=469771 JSU10_RS09900 WP_000611335.1 2069394..2070050(+) (letA) [Escherichia coli H20 strain MIN6]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=469771 JSU10_RS09900 WP_000611335.1 2069394..2070050(+) (letA) [Escherichia coli H20 strain MIN6]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486