Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HP2017_RS00095 Genome accession   NC_017374
Coordinates   12177..14540 (+) Length   787 a.a.
NCBI ID   WP_000890239.1    Uniprot ID   -
Organism   Helicobacter pylori 2017     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 7177..19540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HP2017_RS00065 (hp2017_0012) groES 7195..7551 (-) 357 WP_000671927.1 co-chaperone GroES -
  HP2017_RS00070 (hp2017_0013) dnaG 7838..9517 (+) 1680 WP_000601516.1 DNA primase -
  HP2017_RS00075 (hp2017_0014) - 9514..10565 (+) 1052 Protein_9 argininosuccinate synthase domain-containing protein -
  HP2017_RS00080 (hp2017_0015) - 10658..11485 (+) 828 WP_001154977.1 DUF5718 family protein -
  HP2017_RS00085 (hp2017_0016) comB2 11631..11912 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  HP2017_RS00090 (hp2017_0017) comB3 11912..12175 (+) 264 WP_000584948.1 hypothetical protein Machinery gene
  HP2017_RS00095 (hp2017_0018) comB4 12177..14540 (+) 2364 WP_000890239.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HP2017_RS00100 (hp2017_0020) - 14845..16185 (+) 1341 WP_001938079.1 COG3014 family protein -
  HP2017_RS00105 (hp2017_0021) cheV1 16292..17257 (+) 966 WP_000785452.1 chemotaxis protein CheV1 -
  HP2017_RS00110 (hp2017_0022) nspC 17254..18471 (+) 1218 WP_000760918.1 carboxynorspermidine decarboxylase -
  HP2017_RS00115 (hp2017_0023) lpxE 18482..19027 (-) 546 WP_264388584.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90267.58 Da        Isoelectric Point: 7.6534

>NTDB_id=46974 HP2017_RS00095 WP_000890239.1 12177..14540(+) (comB4) [Helicobacter pylori 2017]
MLEKFLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVACLVVKRRKIDYRQSIQSDSQYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSFMHANRENFKDILS
YKVHFLQETFKSLEIQLKNYAPKLLNSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSTHKTLSFLKERAKFSMSSLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNTKEIARVNGHTLVIGATGSGKSTLISYLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=46974 HP2017_RS00095 WP_000890239.1 12177..14540(+) (comB4) [Helicobacter pylori 2017]
ATGCTAGAAAAGTTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTGCTCACTAAAAACGAAAACTTAGTGGGTATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAACGCCAAATGGCTTTGGAT
TCTTTGGAAAAAGTCGTGGCGTGCCTCGTGGTTAAAAGGCGTAAAATTGATTATCGACAAAGCATTCAATCTGACTCTCA
ATACTTGCAAGCGATCTTGAACCAGTTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTGGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGTGCATTTTTTGCAAGAAACTTTTAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAACTC
TAAAGAGGTTTTGAATTTTTACGCAGAATACATTAACGGGTTTGATCTCCCCTTAAAACCCCTAGTAGGAGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAACCAAAAAACCTATAAC
CGCTTGATTGGTATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCACGCATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCTAGTCTCGTTAAAAACGAGCTGCTAGAATACCAGGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACACTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTATTTAATGATGAGTGCTTTAAAATACCAAAACATGCGCCTTTTAGCTTTTGATAGGATGCAAGGGCTG
TATTCTTTTACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTCGATCTCGCCCCCTCAAGAGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTAGCGCGATTAAGAGCCTTTATGAGACCCTATACCCCAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTAAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAATTAAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.315

100

0.963

Multiple sequence alignment