Detailed information NTG0046973

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SAI7S6_RS08550
• Genome accession: NC_020537
• Coordinates: 1762339..1763328 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1757339..1768328

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI7S6_RS08535 (SAI7S6_1012720)	acsA	1758540..1760246 (-)	1707	WP_000862095.1	acetate--CoA ligase	-
SAI7S6_RS08540 (SAI7S6_1012730)	-	1760415..1761047 (+)	633	WP_015445864.1	hypothetical protein	-
SAI7S6_RS08545 (SAI7S6_1012740)	-	1761072..1762241 (+)	1170	WP_001184015.1	acetoin utilization protein AcuC	-
SAI7S6_RS08550 (SAI7S6_1012750)	ccpA	1762339..1763328 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
SAI7S6_RS14685	-	1763401..1763514 (-)	114	WP_001788994.1	hypothetical protein	-
SAI7S6_RS08560 (SAI7S6_1012760)	-	1763868..1764959 (-)	1092	WP_000066374.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
SAI7S6_RS14690	-	1765414..1765497 (-)	84	WP_031761406.1	hypothetical protein	-
SAI7S6_RS08570 (SAI7S6_1012770)	-	1765653..1767011 (-)	1359	WP_000193903.1	hypothetical protein	-
SAI7S6_RS08575 (SAI7S6_1012780)	-	1767085..1767576 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=46973 SAI7S6_RS08550 WP_000219066.1 1762339..1763328(-) (ccpA) [Staphylococcus aureus subsp. aureus ST228]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=46973 SAI7S6_RS08550 WP_000219066.1 1762339..1763328(-) (ccpA) [Staphylococcus aureus subsp. aureus ST228]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCTAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462