Detailed information NTG0469386

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: FOLKNPGA_RS11105
• Genome accession: NZ_CP059400
• Coordinates: 2520204..2522942 (+)
• Length: 912 a.a.
• NCBI ID: WP_182352839.1
• Uniprot ID: -
• Organism: Legionella sp. PC1000
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2515204..2527942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOLKNPGA_RS11085 (FOLKNPGA_02251)	gstA	2515213..2515815 (-)	603	WP_182349970.1	glutathione transferase GstA	-
FOLKNPGA_RS11090 (FOLKNPGA_02252)	-	2515919..2516860 (-)	942	WP_370529165.1	hypothetical protein	-
FOLKNPGA_RS11095 (FOLKNPGA_02253)	-	2517101..2518363 (-)	1263	WP_182349972.1	serine hydrolase	-
FOLKNPGA_RS11100 (FOLKNPGA_02254)	gltX	2518480..2519895 (-)	1416	WP_182349973.1	glutamate--tRNA ligase	-
FOLKNPGA_RS11105 (FOLKNPGA_02255)	letS	2520204..2522942 (+)	2739	WP_182352839.1	two-component system sensor histidine kinase LetS	Regulator
FOLKNPGA_RS11110 (FOLKNPGA_02256)	-	2523142..2524386 (+)	1245	WP_182349974.1	6-phosphofructokinase	-
FOLKNPGA_RS11115 (FOLKNPGA_02257)	pilA	2524757..2525188 (+)	432	WP_220471037.1	pilin	Machinery gene
FOLKNPGA_RS11120 (FOLKNPGA_02258)	-	2525260..2525589 (+)	330	WP_182349975.1	BolA family transcriptional regulator	-
FOLKNPGA_RS11125 (FOLKNPGA_02259)	-	2525976..2527376 (+)	1401	WP_182349976.1	APC family permease	-
FOLKNPGA_RS11130 (FOLKNPGA_02260)	-	2527454..2527633 (-)	180	WP_019231979.1	Trm112 family protein	-

Sequence

Protein

• Length: 912 a.a.
• Molecular weight: 103162.59 Da
• Isoelectric Point: 7.2568

>NTDB_id=469386 FOLKNPGA_RS11105 WP_182352839.1 2520204..2522942(+) (letS) [Legionella sp. PC1000]
MLKSIGIKYQLRITTLIPAFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRRDDRTLQGLINASTINP
EVIALAFYSSDGQLLAYRGGKHSLNKPFNPPKFTGDYIESKQINPFTINFIAPVTIPKFNLYSNSSFQNLLSPMATRADD
ILGWLSIDIDTRSMIIKRYQMLIVTIFITLFGLLMGLTIHYFLSKKIYLPISRLRRSMKQILRNEFETEIKTTSPGELGT
IEQGCAHLQKKYLETVRDLNQHIEVATEDLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKTSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLTLAAPNAHKKGIDLIPITD
INVPKIILGDPFRIKQFITNLVTNAVKFTDHGYVLVRTKVEQETDRDYTLCITITDTGLGISPEDQSKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRITFTSELNKGSSFTAHVKVEKLVAYEIEKNQIHPFAHYKMLCFDDNSLHLEALCNG
LGYWGIQCVPVNSLNHLEKALENNKDCKIAFLNINKGYEQKIAKIISEHNYFPYVLISKWLINDYTALGGQGFLYKPISI
QKLQDVIESLTSLENIEKPVNHELDSLREQLRFMHPDLLIAEDNPVNKMLLNSLLGTHANMTSVDDGEMAVSACNDKKYD
LILLDLQMPKINGLEAARLIRQKSQLNRHTPIVLISANGSDVNSIDLKKAGVDYCLQKPIDEKQLLTQILRIADKSKHAA
IDWQLCVQKVSGNQVLAEEFLARFVEELHKNREEFIQLMHDKNIKKLGEAAHKLHGACCFSGVPTLQKKVVHVEKLAVHA
ASIEELATPFAELIQSIDAVINEYENQKIRVN

Nucleotide

• Length: 2739 bp

>NTDB_id=469386 FOLKNPGA_RS11105 WP_182352839.1 2520204..2522942(+) (letS) [Legionella sp. PC1000]
ATTTTGAAAAGCATTGGTATTAAGTATCAACTGAGAATTACTACCCTAATCCCAGCCTTTTTAGTCGCCCTGCTTCTCGC
TATTTTTTATAATGGACTATTTGGTAATGACTTAAAACAACATATGTCGCGTTTGGGAGAAGCTTATATCCGTCAATTGC
TTCCTGCCGCTCAATACGCCATGCTCCGACGCGATGATCGTACTTTGCAAGGTTTAATTAATGCTTCTACAATTAACCCG
GAAGTAATAGCTCTAGCCTTTTACAGTAGTGATGGGCAATTGCTAGCCTATCGTGGTGGGAAACACTCGCTGAATAAGCC
ATTTAATCCACCTAAATTTACAGGGGATTACATTGAAAGTAAGCAAATTAATCCTTTCACTATTAATTTCATCGCACCAG
TTACCATTCCTAAATTTAATCTTTACTCCAATTCATCCTTCCAGAACCTACTGAGTCCTATGGCTACTCGTGCAGATGAT
ATTTTAGGTTGGTTATCCATTGATATTGATACGCGCTCGATGATTATAAAGCGCTATCAAATGCTCATAGTAACGATTTT
TATTACCCTATTTGGCTTGCTTATGGGATTAACCATTCACTATTTTCTGTCCAAGAAGATTTATTTACCTATTTCTCGTT
TACGTAGAAGTATGAAACAAATTTTGCGAAATGAATTCGAAACGGAAATAAAAACAACCAGTCCCGGTGAACTAGGTACT
ATTGAGCAAGGTTGTGCCCATTTACAAAAAAAATACCTCGAGACAGTTCGTGATTTAAATCAACATATTGAAGTAGCCAC
CGAAGATTTGCAGCAAAGTCTTGAGCTGTTAGAAGAAAAAAATATCGAACTATCACTCGAGAAGAAAAAAATAGAAGAAA
AAAGTCGGCAAAAATCAGAATTTATTGCCAATATGAGTCATGAAATCCGCACACCAATGAACGGAGTAATTGGTTTCACT
AATGTTTTACTGGAAAGCAAACTTGATCCATTGCAATTGGATTATGTAAAAACGATAAAAACTTCTGCACAAGATTTATT
AGGAATAATTAACGACATTCTCGATTTTTCCAAAATCGATGCTGGAAAACTTCATCTGGATTGCATCCCATTAAATATTC
GTCATTGCATTGATGAAGTCCTTACACTCGCGGCACCGAATGCACATAAAAAAGGAATTGATTTAATCCCCATAACCGAC
ATTAATGTACCCAAAATTATTTTGGGAGATCCCTTCAGAATAAAACAATTTATCACCAACTTGGTAACCAACGCCGTTAA
ATTTACAGATCATGGTTATGTGTTGGTTCGCACCAAAGTAGAACAGGAAACAGATAGAGATTATACTTTATGCATCACAA
TTACAGATACCGGTCTGGGTATTTCTCCCGAAGATCAAAGTAAATTGTTTACGGCATTTAACCAAGCGGATACAAGCATT
ACGCGACGTTATGGCGGTTCAGGCCTTGGTTTAGTTATTTGCAAAAAACTCTGTGAAGAAATGCATGGTCGGATTACATT
TACAAGTGAACTCAATAAAGGCTCTAGCTTTACTGCCCATGTCAAAGTCGAAAAGCTGGTTGCTTATGAAATAGAAAAAA
ACCAAATACACCCCTTTGCCCATTACAAAATGCTGTGCTTTGACGATAATTCCCTGCACTTGGAAGCTCTGTGTAATGGC
TTAGGCTATTGGGGAATACAATGCGTCCCTGTAAATTCGTTGAACCACCTTGAAAAAGCCCTGGAGAATAATAAAGACTG
TAAAATTGCTTTTCTCAATATTAATAAAGGCTACGAGCAAAAAATCGCTAAAATTATCTCAGAGCATAATTACTTTCCTT
ATGTATTGATTTCCAAATGGCTTATTAATGATTACACCGCGCTTGGTGGTCAAGGCTTTTTATATAAACCAATTAGTATT
CAGAAACTCCAAGACGTTATTGAATCACTTACTAGCCTAGAAAATATTGAAAAGCCAGTCAATCATGAATTGGATAGCTT
AAGGGAACAATTACGTTTTATGCATCCAGATTTGCTTATTGCCGAAGACAACCCCGTTAATAAAATGCTTTTGAACTCTT
TATTAGGCACCCACGCAAACATGACTTCAGTTGATGATGGTGAGATGGCTGTATCTGCATGCAATGACAAAAAATATGAC
TTGATTTTACTTGACTTACAAATGCCGAAAATAAATGGTTTAGAAGCAGCTCGACTCATTCGTCAAAAATCGCAACTTAA
CCGTCATACCCCTATAGTTTTGATTAGCGCGAATGGCAGTGATGTAAATAGTATTGATCTGAAAAAAGCAGGTGTTGACT
ATTGCTTACAAAAGCCTATAGATGAAAAACAATTACTTACACAAATTCTTCGTATTGCAGATAAATCAAAACATGCGGCA
ATCGACTGGCAATTATGTGTACAAAAAGTATCAGGAAATCAAGTGCTTGCGGAAGAATTCCTTGCACGATTTGTTGAAGA
GCTCCATAAAAATCGTGAAGAATTCATCCAGTTAATGCATGATAAAAACATTAAAAAATTAGGAGAAGCAGCACATAAAC
TTCACGGGGCATGCTGTTTTTCCGGAGTACCCACGTTACAGAAAAAAGTAGTTCATGTAGAAAAACTGGCGGTACATGCT
GCTTCAATTGAAGAATTAGCCACCCCTTTTGCAGAGTTAATTCAAAGTATTGATGCAGTAATTAATGAGTACGAAAATCA
GAAAATCAGAGTTAACTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Hpt domain (Hpt) (819-901)

• Single cache domain 4 (sCache_4) (36-180)

• Response regulator receiver domain (Response_reg) (679-789)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	79.162	99.452	0.787