Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6J89_RS11775 Genome accession   NZ_CP069559
Coordinates   2483051..2483707 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1259     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2478051..2488707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J89_RS11745 (I6J89_11745) dcyD 2478930..2479916 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  I6J89_RS11750 (I6J89_11750) tcyL 2479931..2480599 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6J89_RS11755 (I6J89_11755) tcyN 2480596..2481348 (+) 753 WP_001272998.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6J89_RS11760 (I6J89_11760) sdiA 2481578..2482300 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6J89_RS11765 (I6J89_11765) yecF 2482368..2482592 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6J89_RS11770 (I6J89_11770) yecU 2482579..2482755 (-) 177 WP_001307856.1 protein YecU -
  I6J89_RS11775 (I6J89_11775) letA 2483051..2483707 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6J89_RS11780 (I6J89_11780) uvrC 2483704..2485536 (+) 1833 WP_045233244.1 excinuclease ABC subunit UvrC Machinery gene
  I6J89_RS11785 (I6J89_11785) pgsA 2485593..2486141 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6J89_RS11805 (I6J89_11805) yecA 2486790..2487455 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=468249 I6J89_RS11775 WP_000611328.1 2483051..2483707(+) (letA) [Escherichia coli strain FDAARGOS_1259]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=468249 I6J89_RS11775 WP_000611328.1 2483051..2483707(+) (letA) [Escherichia coli strain FDAARGOS_1259]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482