Detailed information NTG0046813

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HPSA_RS01655
• Genome accession: NC_017361
• Coordinates: 343008..343808 (+)
• Length: 266 a.a.
• NCBI ID: WP_000840108.1
• Uniprot ID: E8QV74
• Organism: Helicobacter pylori SouthAfrica7
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 338008..348808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSA_RS01620 (HPSA_01665)	pseH	338501..339043 (+)	543	WP_000742578.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
HPSA_RS01625 (HPSA_01670)	-	338976..339914 (-)	939	WP_000833861.1	tetraacyldisaccharide 4'-kinase	-
HPSA_RS01630 (HPSA_01675)	-	339911..340693 (-)	783	WP_001169108.1	NAD+ synthase	-
HPSA_RS01640 (HPSA_01685)	ilvC	340950..341942 (+)	993	WP_001207814.1	ketol-acid reductoisomerase	-
HPSA_RS01645 (HPSA_01690)	minD	341965..342771 (+)	807	WP_001029121.1	septum site-determining protein MinD	-
HPSA_RS01650 (HPSA_01695)	minE	342768..343001 (+)	234	WP_000051430.1	cell division topological specificity factor MinE	-
HPSA_RS01655 (HPSA_01700)	dprA	343008..343808 (+)	801	WP_000840108.1	DNA-processing protein DprA	Machinery gene
HPSA_RS01660	ruvX	343805..344208 (+)	404	Protein_316	Holliday junction resolvase RuvX	-
HPSA_RS01665 (HPSA_01710)	-	344529..345122 (+)	594	WP_144290584.1	tetratricopeptide repeat protein	-
HPSA_RS01670 (HPSA_01715)	-	345237..345575 (+)	339	WP_000699877.1	hypothetical protein	-
HPSA_RS01675 (HPSA_01720)	-	345559..346119 (+)	561	WP_001035856.1	hypothetical protein	-
HPSA_RS01680 (HPSA_01725)	-	346205..347086 (-)	882	WP_001117220.1	RluA family pseudouridine synthase	-
HPSA_RS01685 (HPSA_01730)	recJ	347086..348636 (-)	1551	WP_000810808.1	single-stranded-DNA-specific exonuclease RecJ	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29899.60 Da
• Isoelectric Point: 7.3764

>NTDB_id=46813 HPSA_RS01655 WP_000840108.1 343008..343808(+) (dprA) [Helicobacter pylori SouthAfrica7]
MKSNFQYSALENIPKAFDILKDPPKKLYFIGNTELLDAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPTTIMLSPCSLDFVYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDVVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIYHFINTLLKDYHLQEINENKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRVNHLVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=46813 HPSA_RS01655 WP_000840108.1 343008..343808(+) (dprA) [Helicobacter pylori SouthAfrica7]
ATGAAAAGTAATTTCCAATATAGCGCGCTAGAGAATATCCCTAAAGCCTTTGACATCCTCAAAGACCCCCCTAAAAAGCT
CTATTTTATAGGCAATACCGAGCTTTTGGATGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCCAAAAATGGCGCGGTTATTGTGAGTGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAACAACGATCATGCTTTCGCCTTGCAGTTTGGATTTTGTCTATCCTACCAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTCATGCCCATTAAAG
GCTCTTTTTTAGCGAGAAACCGCTTAGTGATCGCTTTAAGCGATGTGGTGATTATCCCCCAAGCGGATTTGAAAAGCGGC
TCTATGAGCAGCGCGAGATTAGCCCAAAAATACCAAAAACCCCTATTTGTTTTGCCCCAACGCCTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTTATCATTTTATAAACACCCTTTTAAAAGACT
ATCATTTACAAGAAATAAATGAAAATAAAGATGAATTTTTAGAATATTGCGCGAAAAACCCTAGCTATGAAGAAGCGTAT
CTCAAATTTGGGGATAAACTTTTAGAATACGAGCTATTAGGTAAGATCAAGCGCGTCAATCATCTCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (12-197)

3D structure

• AlphaFold DB: E8QV74

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	93.233	100	0.932
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.472	86.09	0.417