Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6J38_RS04705 Genome accession   NZ_CP069558
Coordinates   955440..957218 (-) Length   592 a.a.
NCBI ID   WP_022525610.1    Uniprot ID   U2YBT7
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 950440..962218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS04680 (I6J38_04680) - 950498..951082 (-) 585 WP_003068457.1 uracil-DNA glycosylase family protein -
  I6J38_RS04685 (I6J38_04685) - 951092..951949 (-) 858 WP_006268322.1 SDR family oxidoreductase -
  I6J38_RS04690 (I6J38_04690) pepV 952005..953405 (-) 1401 WP_006268246.1 dipeptidase PepV -
  I6J38_RS04695 (I6J38_04695) - 953425..954030 (-) 606 WP_006268501.1 nitroreductase family protein -
  I6J38_RS04700 (I6J38_04700) - 954427..955251 (-) 825 WP_020997960.1 hypothetical protein -
  I6J38_RS04705 (I6J38_04705) uvrC 955440..957218 (-) 1779 WP_022525610.1 excinuclease ABC subunit UvrC Machinery gene
  I6J38_RS04710 (I6J38_04710) ptsP 957598..959331 (-) 1734 WP_003068445.1 phosphoenolpyruvate--protein phosphotransferase -
  I6J38_RS04715 (I6J38_04715) - 959333..959596 (-) 264 WP_003023815.1 phosphocarrier protein HPr -
  I6J38_RS04720 (I6J38_04720) nrdH 959990..960208 (+) 219 WP_006269677.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 592 a.a.        Molecular weight: 68261.68 Da        Isoelectric Point: 9.4089

>NTDB_id=468128 I6J38_RS04705 WP_022525610.1 955440..957218(-) (uvrC) [Streptococcus constellatus strain FDAARGOS_1208]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIEDFEFIVTESNIEALLLEIN
LIKENQPKYNIVLKDDKSYPFIKITNEIYPRLIITRQVKKDGGWYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTICHNEQHFFQNMAQEVADFLKGHDNKIIDELKGKMTSAAEKMEFEKAAEYRDLLQSIATLRTKQRVMAR
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIKRDVNMFPYYNDPDEDFLTYIGQFYQEKSHLIPNEILIPSDIDEESVRAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGRLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNVAKDVIQHQLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMRHFKSL
ANIKKASVEEIVEVGVPRKVAEAVQTKLHLEV

Nucleotide


Download         Length: 1779 bp        

>NTDB_id=468128 I6J38_RS04705 WP_022525610.1 955440..957218(-) (uvrC) [Streptococcus constellatus strain FDAARGOS_1208]
ATGAACAACTTGATTAAATCAAAATTGGAATTATTGCCGACTAGCCCAGGCTGTTATATCCACAAGGATAAAAATGGTAC
GATCATATATGTAGGAAAAGCCAAGAATCTGCGCAATCGGGTGCGCTCGTATTTTCGCGGAAGTCATGATACTAAAACGG
AAGCACTGGTGTCTGAGATTGAGGATTTTGAGTTTATTGTCACGGAGTCTAACATTGAAGCCTTGCTGCTTGAAATCAAT
CTAATCAAGGAAAATCAGCCTAAGTACAACATCGTGCTCAAAGATGATAAGTCCTACCCTTTTATCAAAATCACCAATGA
GATATATCCGCGACTTATTATTACGCGTCAGGTCAAGAAAGACGGTGGTTGGTATTTCGGCCCTTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCTTGCTGGATCGAATTTTCCCTTTTCGCAAATGCACCAATCCGCCTGAGAAGGTTTGTTTC
TACTACCATATCGGACAGTGCCGAGCTCACACTATTTGCCATAATGAGCAGCATTTTTTTCAAAATATGGCTCAGGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAGTACCGCGACTTACTTCAAAGTATTGCGACGCTTCGCACTAAGCAACGAGTGATGGCAAGA
GATTTGCAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTAAGCGAGATGTGAATATGTTTCCTTATTACAATGATCCCGATGAGGATTTTCTGACCTATATTGGTCAAT
TTTATCAGGAAAAATCTCATCTGATTCCCAATGAAATTTTGATTCCATCTGATATTGACGAGGAATCAGTACGGGCTGTG
GTGGATACAAAAATTCTCAAGCCTCAACGAGGAGAAAAGAAACAGCTGGTCAATCTGGCAATTAAGAATGCTCAAGTTAG
TTTACAGCAGAAGTTTGACTTATTAGAGAAATCTGTTGAAAAAACGCAAGGAGCAATTGAAAATCTAGGCCGGCTCCTCA
ATATTCCCACTCCAGTTCGGATTGAGTCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATTAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCGGATGACTATGCCAG
TATGCGGGAAGTCATCAAGCGTCGCTACAGCCGAGTTATGCGAGATGGTTTAATACCGCCTGATCTGATTGTCATTGATG
GTGGTCAGGGCCAAGTCAACGTTGCTAAAGACGTCATTCAACATCAATTAGGTTTAGATATTCCTATCGCTGGTTTGCAA
AAGAACGACAAGCATCAGACTCATGAATTACTTTTTGGTGATCCATTGGAAGTGGTCGAATTATCTCGCAATTCACAGGA
ATTTTTCCTTTTGCAGCGCATCCAAGATGAAGTCCACCGCTTTGCCATTACCTTCCATCGCCAGCTCCGGTCTAAGAATT
CCTTCTCATCACAACTAGATGGTATTGAAGGACTGGGGCCCAAACGCAAGCAAAATCTGATGCGACATTTTAAATCTTTG
GCCAATATCAAGAAAGCTAGTGTTGAGGAAATTGTCGAAGTAGGCGTACCGCGAAAAGTTGCAGAGGCCGTGCAGACCAA
GCTTCACCTAGAAGTCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(538-585)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2YBT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

88.795

99.493

0.883
  uvrC Streptococcus pneumoniae D39

88.795

99.493

0.883
  uvrC Streptococcus pneumoniae TIGR4

88.795

99.493

0.883