Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6J38_RS00065 Genome accession   NZ_CP069558
Coordinates   13600..14232 (+) Length   210 a.a.
NCBI ID   WP_006267191.1    Uniprot ID   F9P4H6
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8600..19232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS00045 (I6J38_00045) - 9025..9765 (+) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6J38_RS00050 (I6J38_00050) stkP 9762..11645 (+) 1884 WP_020997630.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6J38_RS00055 (I6J38_00055) liaF 11908..12606 (+) 699 WP_020997631.1 cell wall-active antibiotics response protein LiaF -
  I6J38_RS00060 (I6J38_00060) - 12603..13598 (+) 996 WP_006267397.1 sensor histidine kinase -
  I6J38_RS00065 (I6J38_00065) vraR 13600..14232 (+) 633 WP_006267191.1 response regulator transcription factor Regulator
  I6J38_RS00070 (I6J38_00070) - 14279..15679 (+) 1401 WP_020997632.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6J38_RS00075 (I6J38_00075) - 15681..16073 (+) 393 WP_020997633.1 S1 RNA-binding domain-containing protein -
  I6J38_RS00080 (I6J38_00080) - 16193..16510 (-) 318 WP_006269734.1 DUF960 domain-containing protein -
  I6J38_RS00085 (I6J38_00085) - 16630..17163 (-) 534 WP_003070217.1 nucleoside tri-diphosphate phosphatase -
  I6J38_RS00090 (I6J38_00090) recX 17250..18026 (-) 777 WP_006267569.1 recombination regulator RecX Regulator
  I6J38_RS00095 (I6J38_00095) - 18090..18866 (-) 777 WP_006267458.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23646.27 Da        Isoelectric Point: 4.7982

>NTDB_id=468086 I6J38_RS00065 WP_006267191.1 13600..14232(+) (vraR) [Streptococcus constellatus strain FDAARGOS_1208]
MQILLVDDHEMVRLGLKSYLDLQDDVDVVVEASNGREGVEKALALRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=468086 I6J38_RS00065 WP_006267191.1 13600..14232(+) (vraR) [Streptococcus constellatus strain FDAARGOS_1208]
ATGCAGATTTTATTAGTAGATGACCATGAGATGGTACGACTTGGCTTGAAAAGTTATTTGGATTTACAAGATGATGTTGA
TGTAGTGGTAGAAGCTTCAAACGGTCGTGAAGGAGTTGAAAAAGCTTTAGCATTACGACCAGATGTTATTATGATGGATA
TTGTTATGCCTGAAATGAGTGGAATTGAAGCAACTCTAGCTATTTTAAAAGAATGGCCTGAAGCTAAGATTCTCATTCTG
ACTTCTTATTTGGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGAGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTTGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGACTACTGGCGAAGGGGTAT
GAAAATCAACGCATAGCAGATGAGTTGTTTATTTCTTTAAAGACAGTGAAAACGCATGTGTCGAATATTTTGTCCAAATT
GGCAGTAAGTGATCGTACACAAGCTGTTGTCTATGCCTTCCAGCATCACCTCGTCCCACAGGATGATATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P4H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414