Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6J98_RS09250 Genome accession   NZ_CP069501
Coordinates   1943242..1943898 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1268     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1938242..1948898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J98_RS09220 (I6J98_09215) dcyD 1939123..1940109 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  I6J98_RS09225 (I6J98_09220) tcyL 1940124..1940792 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6J98_RS09230 (I6J98_09225) tcyN 1940789..1941541 (+) 753 WP_063624912.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6J98_RS09235 (I6J98_09230) sdiA 1941771..1942493 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6J98_RS09240 (I6J98_09235) yecF 1942560..1942784 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6J98_RS09245 (I6J98_09240) yecU 1942771..1942947 (-) 177 WP_032245964.1 protein YecU -
  I6J98_RS09250 (I6J98_09245) letA 1943242..1943898 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6J98_RS09255 (I6J98_09250) uvrC 1943895..1945727 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6J98_RS09260 (I6J98_09255) pgsA 1945784..1946332 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6J98_RS09280 (I6J98_09275) yecA 1946982..1947647 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=467599 I6J98_RS09250 WP_000611328.1 1943242..1943898(+) (letA) [Escherichia coli strain FDAARGOS_1268]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=467599 I6J98_RS09250 WP_000611328.1 1943242..1943898(+) (letA) [Escherichia coli strain FDAARGOS_1268]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482