Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6J88_RS04090 Genome accession   NZ_CP069500
Coordinates   685738..686394 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1258     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 680738..691394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J88_RS04060 (I6J88_04065) yecA 681990..682655 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  I6J88_RS04080 (I6J88_04085) pgsA 683304..683852 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6J88_RS04085 (I6J88_04090) uvrC 683909..685741 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6J88_RS04090 (I6J88_04095) letA 685738..686394 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6J88_RS04095 (I6J88_04100) yecU 686690..686866 (+) 177 WP_001307856.1 protein YecU -
  I6J88_RS04100 (I6J88_04105) yecF 686853..687077 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6J88_RS04105 (I6J88_04110) sdiA 687145..687867 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6J88_RS04110 (I6J88_04115) tcyN 688097..688849 (-) 753 WP_001272998.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6J88_RS04115 (I6J88_04120) tcyL 688846..689514 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  I6J88_RS04120 (I6J88_04125) dcyD 689529..690515 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=467488 I6J88_RS04090 WP_000611328.1 685738..686394(-) (letA) [Escherichia coli strain FDAARGOS_1258]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=467488 I6J88_RS04090 WP_000611328.1 685738..686394(-) (letA) [Escherichia coli strain FDAARGOS_1258]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482