Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPV225_RS00105 Genome accession   NC_017355
Coordinates   14008..16371 (+) Length   787 a.a.
NCBI ID   WP_000890543.1    Uniprot ID   -
Organism   Helicobacter pylori v225d     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9008..21371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPV225_RS00075 (HPV225_0015) groES 9036..9392 (-) 357 WP_000671943.1 co-chaperone GroES -
  HPV225_RS00080 (HPV225_0016) dnaG 9667..11346 (+) 1680 WP_000601550.1 DNA primase -
  HPV225_RS00085 (HPV225_0017) - 11343..12395 (+) 1053 WP_000802578.1 MnmA/TRMU family protein -
  HPV225_RS00090 (HPV225_0019) - 12487..13314 (+) 828 WP_001154895.1 DUF5718 family protein -
  HPV225_RS00095 (HPV225_0020) comB2 13462..13743 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPV225_RS00100 (HPV225_0021) comB3 13743..14006 (+) 264 WP_000584977.1 hypothetical protein Machinery gene
  HPV225_RS00105 (HPV225_0022) comB4 14008..16371 (+) 2364 WP_000890543.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPV225_RS00110 (HPV225_0025) - 16691..18031 (+) 1341 WP_041169163.1 COG3014 family protein -
  HPV225_RS00115 (HPV225_0026) cheV1 18127..19092 (+) 966 WP_000785499.1 chemotaxis protein CheV1 -
  HPV225_RS00120 (HPV225_0027) nspC 19089..20306 (+) 1218 WP_000760890.1 carboxynorspermidine decarboxylase -
  HPV225_RS00125 (HPV225_0028) lpxE 20316..20849 (-) 534 WP_238523870.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90263.77 Da        Isoelectric Point: 8.8762

>NTDB_id=46723 HPV225_RS00105 WP_000890543.1 14008..16371(+) (comB4) [Helicobacter pylori v225d]
MLEKLLSAVKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQSDSKYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLRPLVGGYLSDSYIASSTTFEKDYFLQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTMSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFEKQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLRS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=46723 HPV225_RS00105 WP_000890543.1 14008..16371(+) (comB4) [Helicobacter pylori v225d]
ATGTTAGAAAAGCTTTTGAGCGCTGTCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTGCTCACTAAAAACGAAAACTTAGTGGGAATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAATCTGATTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACAC
ACTCTTTACAAGGCGTTTTAGAGCATAAGAAAAAATCTTTAATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTACGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCTTTAAGGCCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTACCACTTTTGAAAAAGATTATTTCCTTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAAACGCC
CTTAGACATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGATGAGTTTTTTAAAAGAGAGGGCCAAATTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAGCTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACGCTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAGGGTGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACTTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAAGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTGGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGCTTGGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGTGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGCTAGATTTT
AAAGAGACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGATGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGACACTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTAGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTAGTGGTGTTGGCTTTGCAAGATATTTACCAATTGAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCG
TTTTTAGAAAACACCCCTTTGTATGCTAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAATTCTAACATGATTGATGT
GAGTTTGGAAAGTTTAGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGTCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAGAAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.967

100

0.98

Multiple sequence alignment