Detailed information NTG0466949

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: I6J85_RS18645
• Genome accession: NZ_CP069447
• Coordinates: 3909949..3911223 (-)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain FDAARGOS_1255
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3904949..3916223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J85_RS18635 (I6J85_18635)	hupB	3906926..3907198 (-)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-
I6J85_RS18640 (I6J85_18640)	lon	3907407..3909761 (-)	2355	WP_001295325.1	endopeptidase La	-
I6J85_RS18645 (I6J85_18645)	clpX	3909949..3911223 (-)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
I6J85_RS18650 (I6J85_18650)	clpP	3911349..3911972 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
I6J85_RS18655 (I6J85_18655)	tig	3912218..3913516 (-)	1299	WP_204083417.1	trigger factor	-
I6J85_RS18660 (I6J85_18660)	bolA	3913860..3914177 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
I6J85_RS18665 (I6J85_18665)	yajG	3914482..3915060 (+)	579	WP_001295326.1	lipoprotein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=466949 I6J85_RS18645 WP_000130305.1 3909949..3911223(-) (clpX) [Escherichia coli strain FDAARGOS_1255]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=466949 I6J85_RS18645 WP_000130305.1 3909949..3911223(-) (clpX) [Escherichia coli strain FDAARGOS_1255]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATTGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAACAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTTATCTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCATCGTGTAGAAACCGGTTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGTCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533