Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H0A38_RS09320 Genome accession   NZ_CP059048
Coordinates   1922377..1923078 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain LAC460     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1917377..1928078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0A38_RS09300 (H0A38_09245) - 1917487..1918704 (-) 1218 WP_033899923.1 cysteine desulfurase -
  H0A38_RS09305 (H0A38_09250) sufD 1918704..1919960 (-) 1257 WP_017864923.1 Fe-S cluster assembly protein SufD -
  H0A38_RS09310 (H0A38_09255) sufC 1920098..1920868 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  H0A38_RS09315 (H0A38_09260) - 1921043..1922374 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  H0A38_RS09320 (H0A38_09265) mecA 1922377..1923078 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  H0A38_RS09325 (H0A38_09270) - 1923208..1923942 (-) 735 WP_058203972.1 amino acid ABC transporter ATP-binding protein -
  H0A38_RS09330 (H0A38_09275) - 1923942..1924628 (-) 687 WP_058203973.1 amino acid ABC transporter permease -
  H0A38_RS09335 (H0A38_09280) - 1924775..1925683 (-) 909 WP_003130548.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=466770 H0A38_RS09320 WP_004255173.1 1922377..1923078(-) (mecA) [Lactococcus lactis strain LAC460]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=466770 H0A38_RS09320 WP_004255173.1 1922377..1923078(-) (mecA) [Lactococcus lactis strain LAC460]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97