Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6J91_RS01825 Genome accession   NZ_CP069441
Coordinates   354204..354860 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1261     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 349204..359860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J91_RS01795 (I6J91_01795) yecA 350456..351121 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  I6J91_RS01815 (I6J91_01815) pgsA 351770..352318 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6J91_RS01820 (I6J91_01820) uvrC 352375..354207 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6J91_RS01825 (I6J91_01825) letA 354204..354860 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6J91_RS01830 (I6J91_01830) yecU 355156..355332 (+) 177 WP_001307856.1 protein YecU -
  I6J91_RS01835 (I6J91_01835) yecF 355319..355543 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6J91_RS01840 (I6J91_01840) sdiA 355611..356333 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6J91_RS01845 (I6J91_01845) tcyN 356563..357315 (-) 753 WP_001272998.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6J91_RS01850 (I6J91_01850) tcyL 357312..357980 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  I6J91_RS01855 (I6J91_01855) dcyD 357995..358980 (-) 986 Protein_370 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=466706 I6J91_RS01825 WP_000611328.1 354204..354860(-) (letA) [Escherichia coli strain FDAARGOS_1261]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=466706 I6J91_RS01825 WP_000611328.1 354204..354860(-) (letA) [Escherichia coli strain FDAARGOS_1261]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482