Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN82_RS10510 Genome accession   NZ_CP068830
Coordinates   2198017..2198673 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C018707     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2193017..2203673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN82_RS10480 (JNN82_10480) dcyD 2193897..2194883 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JNN82_RS10485 (JNN82_10485) tcyL 2194898..2195566 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN82_RS10490 (JNN82_10490) tcyN 2195563..2196315 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN82_RS10495 (JNN82_10495) sdiA 2196545..2197267 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  JNN82_RS10500 (JNN82_10500) yecF 2197334..2197558 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN82_RS10505 (JNN82_10505) yecU 2197545..2197721 (-) 177 WP_000590344.1 protein YecU -
  JNN82_RS25960 - 2197759..2197875 (-) 117 WP_023063716.1 hypothetical protein -
  JNN82_RS10510 (JNN82_10510) letA 2198017..2198673 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN82_RS10515 (JNN82_10515) uvrC 2198670..2200502 (+) 1833 WP_060579134.1 excinuclease ABC subunit UvrC Machinery gene
  JNN82_RS10520 (JNN82_10520) pgsA 2200559..2201107 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN82_RS10540 (JNN82_10540) yecA 2201757..2202422 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=463891 JNN82_RS10510 WP_000611328.1 2198017..2198673(+) (letA) [Escherichia coli strain RIVM_C018707]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=463891 JNN82_RS10510 WP_000611328.1 2198017..2198673(+) (letA) [Escherichia coli strain RIVM_C018707]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGTGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482