Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   HW113_RS06435 Genome accession   NZ_CP058312
Coordinates   1262040..1262726 (+) Length   228 a.a.
NCBI ID   WP_112366458.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BLR-DV     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1257040..1267726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW113_RS06400 (HW113_06400) yqeH 1257567..1258667 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  HW113_RS06405 (HW113_06405) aroE 1258681..1259487 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  HW113_RS06410 (HW113_06410) yhbY 1259491..1259781 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  HW113_RS06415 (HW113_06415) nadD 1259784..1260353 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  HW113_RS06420 (HW113_06420) yqeK 1260343..1260927 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  HW113_RS06425 (HW113_06425) rsfS 1260928..1261281 (+) 354 WP_001088022.1 ribosome silencing factor -
  HW113_RS06430 (HW113_06430) - 1261284..1262000 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  HW113_RS06435 (HW113_06435) comEA 1262040..1262726 (+) 687 WP_112366458.1 ComEA family DNA-binding protein Machinery gene
  HW113_RS06440 (HW113_06440) - 1262818..1263279 (+) 462 WP_000439693.1 ComE operon protein 2 -
  HW113_RS06445 (HW113_06445) comEC 1263284..1265485 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HW113_RS06450 (HW113_06450) holA 1265542..1266516 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  HW113_RS06455 (HW113_06455) rpsT 1266561..1266812 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25877.52 Da        Isoelectric Point: 9.3305

>NTDB_id=463692 HW113_RS06435 WP_112366458.1 1262040..1262726(+) (comEA) [Staphylococcus aureus strain BLR-DV]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADLSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=463692 HW113_RS06435 WP_112366458.1 1262040..1262726(+) (comEA) [Staphylococcus aureus strain BLR-DV]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATCTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

97.797

99.561

0.974
  comEA Staphylococcus aureus N315

96.916

99.561

0.965