Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   HW271_RS07465 Genome accession   NZ_CP058258
Coordinates   1525295..1526332 (-) Length   345 a.a.
NCBI ID   WP_178895481.1    Uniprot ID   A0A7H8Z9J2
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1520295..1531332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS07440 (HW271_07440) endA 1521569..1522396 (-) 828 WP_178895476.1 DNA/RNA non-specific endonuclease Machinery gene
  HW271_RS07445 (HW271_07445) - 1522443..1522637 (-) 195 WP_178895477.1 DNA-directed RNA polymerase subunit beta -
  HW271_RS07450 (HW271_07450) murA 1522624..1523910 (-) 1287 WP_178895478.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  HW271_RS07455 (HW271_07455) - 1523926..1524966 (-) 1041 WP_178895479.1 acyltransferase -
  HW271_RS07460 (HW271_07460) - 1525007..1525237 (-) 231 WP_178895480.1 DUF1146 family protein -
  HW271_RS07465 (HW271_07465) sepM 1525295..1526332 (-) 1038 WP_178895481.1 SepM family pheromone-processing serine protease Regulator
  HW271_RS07470 (HW271_07470) coaD 1526316..1526804 (-) 489 WP_178895482.1 pantetheine-phosphate adenylyltransferase -
  HW271_RS07475 (HW271_07475) rsmD 1526794..1527333 (-) 540 WP_178895483.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  HW271_RS07480 (HW271_07480) asnA 1527394..1528386 (-) 993 WP_178895484.1 aspartate--ammonia ligase -
  HW271_RS07485 (HW271_07485) - 1528475..1529158 (-) 684 WP_178895485.1 Bax inhibitor-1/YccA family protein -
  HW271_RS07490 (HW271_07490) - 1529211..1529951 (-) 741 WP_178895486.1 RNA methyltransferase -
  HW271_RS07495 (HW271_07495) - 1529985..1530263 (+) 279 WP_001174501.1 acylphosphatase -
  HW271_RS07500 (HW271_07500) yidC 1530341..1531264 (+) 924 WP_178895487.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37708.13 Da        Isoelectric Point: 7.0247

>NTDB_id=463247 HW271_RS07465 WP_178895481.1 1525295..1526332(-) (sepM) [Streptococcus sp. oral taxon 061 strain F0704]
MKKKTRWPIYLIIGLVITFIAFTVPLPYYIEVPGTSEDIRKVLQVNNQADQEEGSYQFVTVGVKHARLVDLVYAWLTPFT
DIRSAKEMTGGSSDAEFMRINQFYMETSQNMAKYQGLKSAGKEIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
ESSKEMVDYVNSQTLGDKVKVTYQEDGKVKTAEGKIITLENGKNGIGIGLIDRTEVSSYVPIKFSTAGIGGPSAGMMFSL
SIYTQIADPTLRNGRIIAGTGSIDRDGNVGDIGGIDKKVVAAAKKGATVFFAPNNPVTEEAKKANPNAKSNYDTAVEAAE
MIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=463247 HW271_RS07465 WP_178895481.1 1525295..1526332(-) (sepM) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAAGAAAAAAACTAGATGGCCCATATATTTAATCATTGGGCTTGTTATTACTTTTATAGCTTTTACGGTACCCCTGCC
TTATTACATTGAGGTTCCAGGGACTTCAGAAGATATTCGAAAAGTCTTACAAGTCAATAATCAAGCTGACCAAGAGGAAG
GTTCCTATCAATTTGTGACAGTTGGGGTTAAACATGCTAGACTGGTGGACTTGGTTTATGCTTGGCTGACGCCTTTTACG
GATATTCGAAGTGCTAAAGAGATGACAGGTGGTTCTTCAGATGCAGAATTTATGCGAATCAACCAGTTTTACATGGAAAC
TTCGCAAAACATGGCCAAATATCAAGGTCTGAAATCTGCTGGTAAGGAAATAGAGCTCAAATATCTGGGGGTCTATGTTT
TGACTGTGACGGATAACTCGACTTTCAAGGGGATTCTCAATATCGCTGACACCGTGACGGCTGTAAACGATAAGACTTTT
GAAAGCTCCAAGGAGATGGTCGACTACGTCAACTCTCAAACTCTTGGAGACAAGGTTAAGGTTACCTACCAGGAAGACGG
AAAAGTCAAGACTGCTGAAGGAAAAATCATTACTCTGGAAAATGGGAAAAACGGTATTGGAATCGGTTTGATTGACCGCA
CAGAAGTGTCAAGTTATGTGCCAATCAAGTTTTCAACTGCTGGCATTGGTGGTCCGAGTGCTGGAATGATGTTTAGTTTA
TCCATCTATACGCAAATTGCAGACCCTACTCTTCGAAATGGACGAATCATTGCTGGTACAGGAAGTATCGACAGAGATGG
AAATGTTGGTGATATTGGTGGAATTGACAAAAAAGTTGTTGCTGCTGCAAAAAAAGGAGCTACTGTATTCTTTGCTCCAA
ACAATCCAGTAACTGAAGAAGCTAAAAAGGCCAATCCTAATGCTAAAAGTAATTATGACACGGCTGTAGAAGCTGCTGAA
ATGATTAAAACAGACATGAAGATTGTTCCTGTAAAAACACTTCAGGATGCAATTGATTACTTGAAAAACAACCCATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-193)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(230-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8Z9J2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

58.48

99.13

0.58