Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   HW271_RS07440 Genome accession   NZ_CP058258
Coordinates   1521569..1522396 (-) Length   275 a.a.
NCBI ID   WP_178895476.1    Uniprot ID   -
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1516569..1527396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS07425 (HW271_07425) amiA 1517805..1519784 (-) 1980 WP_006150231.1 peptide ABC transporter substrate-binding protein Regulator
  HW271_RS07435 (HW271_07435) - 1520119..1521450 (-) 1332 WP_178895475.1 hemolysin family protein -
  HW271_RS07440 (HW271_07440) endA 1521569..1522396 (-) 828 WP_178895476.1 DNA/RNA non-specific endonuclease Machinery gene
  HW271_RS07445 (HW271_07445) - 1522443..1522637 (-) 195 WP_178895477.1 DNA-directed RNA polymerase subunit beta -
  HW271_RS07450 (HW271_07450) murA 1522624..1523910 (-) 1287 WP_178895478.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  HW271_RS07455 (HW271_07455) - 1523926..1524966 (-) 1041 WP_178895479.1 acyltransferase -
  HW271_RS07460 (HW271_07460) - 1525007..1525237 (-) 231 WP_178895480.1 DUF1146 family protein -
  HW271_RS07465 (HW271_07465) sepM 1525295..1526332 (-) 1038 WP_178895481.1 SepM family pheromone-processing serine protease Regulator
  HW271_RS07470 (HW271_07470) coaD 1526316..1526804 (-) 489 WP_178895482.1 pantetheine-phosphate adenylyltransferase -
  HW271_RS07475 (HW271_07475) rsmD 1526794..1527333 (-) 540 WP_178895483.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -

Sequence

Protein


Download         Length: 275 a.a.        Molecular weight: 30104.64 Da        Isoelectric Point: 9.4585

>NTDB_id=463246 HW271_RS07440 WP_178895476.1 1521569..1522396(-) (endA) [Streptococcus sp. oral taxon 061 strain F0704]
MNKKTRQALIGLLIFLLLSAGSYYIREMQASNNTPQTQVQQKSESPDTPSQELAESVLTDSVKKQIKGSLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGGETVPTVANALMSKATRQYKDREETGNGSTSWTPAGWHQVKNLKGSYNHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQARAEDSTGQNYYEGLVRKALDKNKRVRYRVTLLYATEEDLVPSASQIE
AKSSDGELEFNVVIPNVQKGIRLDYRTGEVTVTKD

Nucleotide


Download         Length: 828 bp        

>NTDB_id=463246 HW271_RS07440 WP_178895476.1 1521569..1522396(-) (endA) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAATAAAAAAACCAGACAGGCCCTCATAGGTCTCCTGATTTTTCTACTTTTGTCGGCAGGAAGTTACTACATAAGAGA
AATGCAGGCTTCCAATAATACACCACAAACACAGGTACAGCAAAAGTCAGAGTCACCTGATACTCCTAGTCAAGAATTGG
CTGAGAGTGTATTGACTGATTCGGTCAAAAAACAAATAAAGGGATCCCTTGAGTGGAATGGAGCAGGTGCCTTTATTGTA
AATGGGAACAAAACCAATCTAGATGCTAAGGTATCAAGTAAACCCTATGCTGATAATAAAACTAAAACTGTAGGTGGTGA
GACCGTTCCTACCGTAGCCAATGCTCTCATGTCAAAAGCAACTCGACAGTATAAGGATCGCGAAGAGACGGGTAATGGTT
CGACCTCTTGGACTCCAGCAGGCTGGCATCAGGTCAAGAACCTAAAAGGAAGTTATAATCACGCTGTAGATAGAGGACAT
TTATTAGGCTATGCCTTGATTGGTGGTCTAGATGGCTTTGATGCATCTACTAGTAATCCTAAAAACATCGCTGTACAAAC
AGCCTGGGCCAACCAAGCTCGCGCAGAAGATTCAACAGGACAAAACTATTATGAAGGTTTAGTTCGAAAAGCGCTAGATA
AGAATAAACGAGTGCGTTACCGCGTTACGCTACTGTATGCGACAGAAGAGGACCTAGTACCTTCTGCCTCTCAAATTGAA
GCAAAATCCTCTGACGGAGAATTGGAGTTTAATGTAGTAATTCCTAATGTTCAAAAGGGAATTCGGTTAGATTACCGAAC
AGGGGAAGTTACGGTTACAAAAGACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

83.942

99.636

0.836
  endA Streptococcus pneumoniae D39

83.942

99.636

0.836
  endA Streptococcus pneumoniae R6

83.942

99.636

0.836
  endA Streptococcus pneumoniae TIGR4

83.942

99.636

0.836