Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HW271_RS06675 Genome accession   NZ_CP058258
Coordinates   1365640..1366329 (-) Length   229 a.a.
NCBI ID   WP_178895370.1    Uniprot ID   A0A7H8Z940
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1360640..1371329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS06650 (HW271_06650) fni 1360697..1361698 (-) 1002 WP_178895365.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  HW271_RS06655 (HW271_06655) - 1361676..1362689 (-) 1014 WP_178895366.1 phosphomevalonate kinase -
  HW271_RS06660 (HW271_06660) mvaD 1362676..1363629 (-) 954 WP_178895367.1 diphosphomevalonate decarboxylase -
  HW271_RS06665 (HW271_06665) mvk 1363611..1364489 (-) 879 WP_178895368.1 mevalonate kinase -
  HW271_RS06670 (HW271_06670) cbpF 1364612..1365544 (-) 933 WP_178895369.1 choline-binding protein CbpF -
  HW271_RS06675 (HW271_06675) covR 1365640..1366329 (-) 690 WP_178895370.1 response regulator transcription factor Regulator
  HW271_RS06680 (HW271_06680) gndA 1366341..1367765 (-) 1425 WP_178895371.1 NADP-dependent phosphogluconate dehydrogenase -
  HW271_RS06685 (HW271_06685) - 1367842..1369287 (-) 1446 WP_178895372.1 cell division site-positioning protein MapZ family protein -
  HW271_RS06690 (HW271_06690) - 1369280..1370458 (-) 1179 WP_178895373.1 class I SAM-dependent RNA methyltransferase -
  HW271_RS06700 (HW271_06700) gpsB 1370941..1371276 (-) 336 WP_006150353.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26778.83 Da        Isoelectric Point: 6.7633

>NTDB_id=463234 HW271_RS06675 WP_178895370.1 1365640..1366329(-) (covR) [Streptococcus sp. oral taxon 061 strain F0704]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFAEQLSRTKPASVIMVL
DHREELQDQVETIQRFAVSYIYKPVIIDDLVARIAAIFRGRDFIDQHCNQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=463234 HW271_RS06675 WP_178895370.1 1365640..1366329(-) (covR) [Streptococcus sp. oral taxon 061 strain F0704]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTAGAAGAGGGACAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTACTGAATG
CTCATCTAGGGGATATGACAGCCCAGGATTTTGCAGAACAGTTGAGTCGGACTAAGCCAGCTTCGGTTATCATGGTCTTG
GACCATCGAGAAGAATTGCAAGACCAAGTTGAAACAATCCAACGTTTTGCTGTTTCATATATCTACAAGCCAGTCATTAT
CGATGATCTAGTGGCTCGTATTGCAGCAATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAATCAGATGAAGGTTC
CAACATCCTATCGCAATCTGCGTATGGATGTAGAACATCATACCGTCTATCGTGGCGAGGAGATGATTGCTCTGACACGT
CGTGAATATGACCTCTTAGCTACTCTTATGGGAAGTAAGAAGGTTTTAACTCGTGAGCAGTTGCTGGAAAGTGTTTGGAA
GTATGAGAGTGCGACCGAAACCAATATCGTCGATGTTTATATCCGTTATCTACGTAGCAAACTTGACGTAAAAGGTCAAA
AGAGCTATATCAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8Z940

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467