Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN43_RS16515 Genome accession   NZ_CP068821
Coordinates   3409849..3410505 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C029952     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3404849..3415505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN43_RS16485 (JNN43_16485) yecA 3406100..3406765 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  JNN43_RS16505 (JNN43_16505) pgsA 3407415..3407963 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN43_RS16510 (JNN43_16510) uvrC 3408020..3409852 (-) 1833 WP_060579134.1 excinuclease ABC subunit UvrC Machinery gene
  JNN43_RS16515 (JNN43_16515) letA 3409849..3410505 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN43_RS26145 - 3410647..3410763 (+) 117 WP_023063716.1 hypothetical protein -
  JNN43_RS16520 (JNN43_16520) yecU 3410801..3410977 (+) 177 WP_000590344.1 protein YecU -
  JNN43_RS16525 (JNN43_16525) yecF 3410964..3411188 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN43_RS16530 (JNN43_16530) sdiA 3411255..3411977 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  JNN43_RS16535 (JNN43_16535) tcyN 3412207..3412959 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN43_RS16540 (JNN43_16540) tcyL 3412956..3413624 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN43_RS16545 (JNN43_16545) dcyD 3413639..3414625 (-) 987 WP_202851955.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=463145 JNN43_RS16515 WP_000611328.1 3409849..3410505(-) (letA) [Escherichia coli strain RIVM_C029952]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=463145 JNN43_RS16515 WP_000611328.1 3409849..3410505(-) (letA) [Escherichia coli strain RIVM_C029952]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGTGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482