Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HWH77_RS16315 Genome accession   NZ_CP058216
Coordinates   3208297..3208953 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain LF01     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3203297..3213953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWH77_RS16285 (HWH77_16290) oppF 3203826..3204743 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HWH77_RS16290 (HWH77_16295) - 3204850..3206037 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  HWH77_RS16295 (HWH77_16300) - 3206155..3206733 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  HWH77_RS16300 (HWH77_16305) spx 3206912..3207307 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HWH77_RS16305 (HWH77_16310) - 3207365..3208021 (-) 657 WP_003155033.1 TerC family protein -
  HWH77_RS19950 (HWH77_16315) - 3208204..3208314 (+) 111 Protein_3179 adaptor protein MecA -
  HWH77_RS16315 (HWH77_16320) mecA 3208297..3208953 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HWH77_RS16320 (HWH77_16325) - 3209104..3210264 (+) 1161 WP_161503321.1 competence protein CoiA family protein -
  HWH77_RS16325 (HWH77_16330) pepF 3210492..3212321 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  HWH77_RS16330 (HWH77_16335) - 3212359..3212526 (-) 168 WP_003155026.1 hypothetical protein -
  HWH77_RS16335 (HWH77_16340) spxH 3212812..3213714 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=462735 HWH77_RS16315 WP_003155032.1 3208297..3208953(+) (mecA) [Bacillus velezensis strain LF01]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=462735 HWH77_RS16315 WP_003155032.1 3208297..3208953(+) (mecA) [Bacillus velezensis strain LF01]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895