Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN47_RS10340 Genome accession   NZ_CP068808
Coordinates   2152718..2153374 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C018699     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2147718..2158374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN47_RS10310 (JNN47_10310) dcyD 2148598..2149584 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JNN47_RS10315 (JNN47_10315) tcyL 2149599..2150267 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN47_RS10320 (JNN47_10320) tcyN 2150264..2151016 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN47_RS10325 (JNN47_10325) sdiA 2151246..2151968 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  JNN47_RS10330 (JNN47_10330) yecF 2152035..2152259 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN47_RS10335 (JNN47_10335) yecU 2152246..2152422 (-) 177 WP_000590344.1 protein YecU -
  JNN47_RS26145 - 2152460..2152576 (-) 117 WP_023063716.1 hypothetical protein -
  JNN47_RS10340 (JNN47_10340) letA 2152718..2153374 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN47_RS10345 (JNN47_10345) uvrC 2153371..2155203 (+) 1833 WP_060579134.1 excinuclease ABC subunit UvrC Machinery gene
  JNN47_RS10350 (JNN47_10350) pgsA 2155260..2155808 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN47_RS10370 (JNN47_10370) yecA 2156458..2157123 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=462015 JNN47_RS10340 WP_000611328.1 2152718..2153374(+) (letA) [Escherichia coli strain RIVM_C018699]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=462015 JNN47_RS10340 WP_000611328.1 2152718..2153374(+) (letA) [Escherichia coli strain RIVM_C018699]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGTGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482