Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN51_RS03980 Genome accession   NZ_CP068807
Coordinates   795758..796414 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C018583     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 790758..801414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN51_RS03950 (JNN51_03950) yecA 792009..792674 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  JNN51_RS03970 (JNN51_03970) pgsA 793324..793872 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN51_RS03975 (JNN51_03975) uvrC 793929..795761 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JNN51_RS03980 (JNN51_03980) letA 795758..796414 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN51_RS26770 - 796556..796672 (+) 117 WP_023063716.1 hypothetical protein -
  JNN51_RS03985 (JNN51_03985) yecU 796710..796886 (+) 177 WP_000590344.1 protein YecU -
  JNN51_RS03990 (JNN51_03990) yecF 796873..797097 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN51_RS03995 (JNN51_03995) sdiA 797164..797886 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  JNN51_RS04000 (JNN51_04000) tcyN 798116..798868 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN51_RS04005 (JNN51_04005) tcyL 798865..799533 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN51_RS04010 (JNN51_04010) dcyD 799548..800534 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=461895 JNN51_RS03980 WP_000611328.1 795758..796414(-) (letA) [Escherichia coli strain RIVM_C018583]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=461895 JNN51_RS03980 WP_000611328.1 795758..796414(-) (letA) [Escherichia coli strain RIVM_C018583]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482